| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9977 | Methylation | CheY - dependent Entitymethylation of the asparagine receptor, EntityMcpB , during chemotaxis in Bacillus subtilis. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | In this study, we show that rapid net Entitydemethylation of B. subtilis EntityMcpB results in the immediate production of methanol, presumably due to the action of CheB. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | We also show that net Entitydemethylation of EntityMcpB occurs upon both addition and removal of asparagine. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | After each demethylation event, EntityMcpB is Entityremethylated to nearly prestimulus levels. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Both Entityremethylation events are attributable to EntityCheR using S - adenosylmethionine as a substrate. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Furthermore, we show that the Entityremethylation of asparagine - bound EntityMcpB requires the response regulator, CheY - P, suggesting that CheY - P acts in a feedback mechanism to facilitate adaptation to positive stimuli during chemotaxis in B. subtilis. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Effect of alternative Entityglycosylation on Entityinsulin receptor processing. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | To examine the importance of EntityN - linked glycosylation on Entityinsulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| 1.0000 | Methylation | To examine the importance of N - linked Entityglycosylation on Entityinsulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| 0.9868 | Methylation | To examine the importance of EntityN - linked glycosylation on Entityinsulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| 0.8955 | Methylation | To examine the importance of EntityN - linked glycosylation Entityglycosylation on insulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| 0.8526 | Methylation | To examine the importance of EntityN - linked glycosylation Entityglycosylation on insulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| 0.7830 | Methylation | To examine the importance of EntityN - linked EntityN - linked glycosylation on insulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| 0.7803 | Methylation | To examine the importance of EntityN - linked Entityglycosylation on insulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| 0.7278 | Methylation | To examine the importance of EntityN - linked Entityglycosylation on insulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| 0.6470 | Methylation | To examine the importance of EntityN - linked glycosylation EntityN - linked glycosylation on insulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9957 | Methylation | N - Glycosidase F treatment shows that the alternative proreceptor contained EntityN - linked Entityoligosaccharides . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | OBJECTIVES : To develop an enzyme - linked immunosorbent assay ( ELISA ) using a monoclonal antibody ( mab ) directed against abnormally Entityglycosylated serum Entityalpha2 - macroglobulin ( alpha2 - M ) from patients with systemic lupus erythematosus ( SLE ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | CONCLUSIONS : The ELISA was capable of recognizing changes of Entityglycosylation of Entityalpha2 - M in SLE and may be useful for its differential diagnosis. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9980 | Methylation | We investigated the kinetics of mRNA induction, demethylation, and Entityremethylation of the p16 Entitypromoter and second - exon CpG islands in T24 cells after 5 - aza - 2'- deoxycytidine ( 5 - Aza - CdR ) treatment to explore the relationship between CpG island methylation and gene transcription. |
| 0.9950 | Methylation | We investigated the kinetics of mRNA induction, demethylation, and Entityremethylation of the p16 promoter and Entitysecond - exon CpG islands in T24 cells after 5 - aza - 2'- deoxycytidine ( 5 - Aza - CdR ) treatment to explore the relationship between CpG island methylation and gene transcription. |
| 0.9943 | Methylation | We investigated the kinetics of mRNA induction, Entitydemethylation , and remethylation of the p16 Entitypromoter and second - exon CpG islands in T24 cells after 5 - aza - 2'- deoxycytidine ( 5 - Aza - CdR ) treatment to explore the relationship between CpG island methylation and gene transcription. |
| 0.9931 | Methylation | We investigated the kinetics of mRNA induction, Entitydemethylation , and remethylation of the p16 promoter and Entitysecond - exon CpG islands in T24 cells after 5 - aza - 2'- deoxycytidine ( 5 - Aza - CdR ) treatment to explore the relationship between CpG island methylation and gene transcription. |
| 0.9788 | Methylation | We investigated the kinetics of mRNA induction, demethylation, and remethylation of the p16 promoter and second - exon CpG islands in T24 cells after 5 - aza - 2'- deoxycytidine ( 5 - Aza - CdR ) treatment to explore the relationship between EntityCpG island Entitymethylation and gene transcription. |
| 0.9921 | Methylation | We investigated the kinetics of mRNA induction, demethylation, and Entityremethylation of the p16 promoter and second - exon EntityCpG islands in T24 cells after 5 - aza - 2'- deoxycytidine ( 5 - Aza - CdR ) treatment to explore the relationship between CpG island methylation and gene transcription. |
| 0.9882 | Methylation | We investigated the kinetics of mRNA induction, Entitydemethylation , and remethylation of the p16 promoter and second - exon EntityCpG islands in T24 cells after 5 - aza - 2'- deoxycytidine ( 5 - Aza - CdR ) treatment to explore the relationship between CpG island methylation and gene transcription. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9988 | Methylation | The rates of remethylation of both CpG islands were associated with time but not with the rate of cell division, and Entityremethylation of the p16 Entityexon 2 CpG island occurred at a higher rate than that of the p16 promoter. |
| 0.9892 | Methylation | The rates of remethylation of both CpG islands were associated with time but not with the rate of cell division, and Entityremethylation of the p16 exon 2 CpG island occurred at a higher rate than that of the p16 Entitypromoter . |
| 0.9999 | Methylation | The rates of Entityremethylation of both EntityCpG islands were associated with time but not with the rate of cell division, and remethylation of the p16 exon 2 CpG island occurred at a higher rate than that of the p16 promoter. |
| 0.9935 | Methylation | The rates of remethylation of both CpG islands were associated with time but not with the rate of cell division, and Entityremethylation of the p16 exon 2 EntityCpG island occurred at a higher rate than that of the p16 promoter. |
| 0.4095 | Methylation | The rates of Entityremethylation of both CpG islands were associated with time but not with the rate of cell division, and remethylation of the p16 Entityexon 2 CpG island occurred at a higher rate than that of the p16 promoter. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | The kinetics of Entityremethylation of the p16 Entityexon 2 , PAX - 6 exon 5, c - ABL exon 11, and MYF - 3 exon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are hypermethylated in T24 cells. |
| 0.9985 | Methylation | The kinetics of remethylation of the p16 exon 2, PAX - 6 exon 5, c - ABL exon 11, and MYF - 3 Entityexon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are Entityhypermethylated in T24 cells. |
| 0.9966 | Methylation | The kinetics of remethylation of the p16 exon 2, PAX - 6 Entityexon 5 , c - ABL exon 11, and MYF - 3 exon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are Entityhypermethylated in T24 cells. |
| 0.9964 | Methylation | The kinetics of remethylation of the p16 exon 2, PAX - 6 exon 5, c - ABL Entityexon 11 , and MYF - 3 exon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are Entityhypermethylated in T24 cells. |
| 0.9959 | Methylation | The kinetics of Entityremethylation of the p16 exon 2, PAX - 6 Entityexon 5 , c - ABL exon 11, and MYF - 3 exon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are hypermethylated in T24 cells. |
| 0.9953 | Methylation | The kinetics of Entityremethylation of the p16 exon 2, PAX - 6 exon 5, c - ABL exon 11, and MYF - 3 Entityexon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are hypermethylated in T24 cells. |
| 0.9943 | Methylation | The kinetics of Entityremethylation of the p16 exon 2, PAX - 6 exon 5, c - ABL Entityexon 11 , and MYF - 3 exon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are hypermethylated in T24 cells. |
| 0.9932 | Methylation | The kinetics of remethylation of the p16 Entityexon 2 , PAX - 6 exon 5, c - ABL exon 11, and MYF - 3 exon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are Entityhypermethylated in T24 cells. |
| 0.9966 | Methylation | The kinetics of remethylation of the p16 exon 2, PAX - 6 exon 5, c - ABL exon 11, and MYF - 3 Entityexon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are Entityhypermethylated in T24 cells. |
| 0.9911 | Methylation | The kinetics of Entityremethylation of the p16 exon 2, PAX - 6 exon 5, c - ABL exon 11, and MYF - 3 Entityexon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are hypermethylated in T24 cells. |
| 0.9892 | Methylation | The kinetics of remethylation of the p16 exon 2, PAX - 6 Entityexon 5, c - ABL exon 11, and MYF - 3 exon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are Entityhypermethylated in T24 cells. |
| 0.9873 | Methylation | The kinetics of Entityremethylation of the p16 exon 2, PAX - 6 Entityexon 5, c - ABL exon 11, and MYF - 3 exon 3 loci were examined following 5 - Aza - CdR treatment because these genes contain exonic CpG islands which are hypermethylated in T24 cells. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | EntityRemethylation occurred most rapidly in the p16, EntityPAX - 6 , and c - ABL genes, shown to be transcribed prior to drug treatment. |
| 0.9996 | Methylation | EntityRemethylation occurred most rapidly in the Entityp16 , PAX - 6, and c - ABL genes, shown to be transcribed prior to drug treatment. |
| 0.9994 | Methylation | EntityRemethylation occurred most rapidly in the p16, PAX - 6, and Entityc - ABL genes, shown to be transcribed prior to drug treatment. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Also, marked relationship of microsatellite instability ( MSI ) and DNA methylation has been reported in sporadic colorectal cancer, which is a result of epigenetic inactivation of hMLH1 in association of Entitypromoter Entityhypermethylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9990 | Methylation | In the present study, we investigated the Entity5'CpG island Entityhypermethylation of hMLH1, E - cadherin and p16 in 61 primary gastric cancers ( GCs ) by using combined bisulfite restriction analysis ( COBRA ) and methylation - specific PCR ( MSP ), and their MSI status. |
| 0.9993 | Methylation | In the present study, we investigated the 5 ' EntityCpG island Entityhypermethylation of hMLH1, E - cadherin and p16 in 61 primary gastric cancers ( GCs ) by using combined bisulfite restriction analysis ( COBRA ) and methylation - specific PCR ( MSP ), and their MSI status. |
| 0.8317 | Methylation | In the present study, we investigated the 5 ' EntityCpG island Entityhypermethylation of hMLH1, E - cadherin and p16 in 61 primary gastric cancers ( GCs ) by using combined bisulfite restriction analysis ( COBRA ) and methylation - specific PCR ( MSP ), and their MSI status. |
| 0.7899 | Methylation | In the present study, we investigated the Entity5'CpG island Entityhypermethylation of hMLH1, E - cadherin and p16 in 61 primary gastric cancers ( GCs ) by using combined bisulfite restriction analysis ( COBRA ) and methylation - specific PCR ( MSP ), and their MSI status. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | Of the 8 MSI - H patients, 5 presented hMLH1 methylation, whereas no low - frequency MSI ( MSI - L ) and microsatellite stable ( MSS ) cases exhibited EntityhMLH1 Entitymethylation ( 5 / 8 vs. 0 / 43, p < 0. 00001 ). |
| 0.9978 | Methylation | Of the 8 MSI - H patients, 5 presented EntityhMLH1 Entitymethylation , whereas no low - frequency MSI ( MSI - L ) and microsatellite stable ( MSS ) cases exhibited hMLH1 methylation ( 5 / 8 vs. 0 / 43, p < 0. 00001 ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Furthermore, these patients also presented EntityE - cadherin and p16 Entityhypermethylation . |
| 0.9979 | Methylation | Furthermore, these patients also presented E - cadherin and Entityp16 Entityhypermethylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9984 | Methylation | Our data showed a significant correlation between EntityhMLH1 Entitymethylation and MSI in GC, and suggested that a common mechanism of aberrant de novo methylation can be postulated in these cancers. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | However, only Entityglycosylated proteins Entity( TSHR - hs and TSHR - gp ) neutralized the TBII activity of sera from autoimmune thyroid patients, confirming the importance of glycosylation for patient autoantibody reactivity. |
| 0.9998 | Methylation | However, only Entityglycosylated proteins ( TSHR - hs and EntityTSHR - gp ) neutralized the TBII activity of sera from autoimmune thyroid patients, confirming the importance of glycosylation for patient autoantibody reactivity. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | BasT - inactivated mutant cells are missing a membrane protein radiolabelled with L - [ methyl - 3H ] - methionine in wild - type cells, confirming that EntityBasT is Entitymethylatable and membrane bound. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Additional EntityN - glycosylation at EntityAsn ( 13 ) rescues the human LHbeta - subunit from disulfide - linked aggregation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Both CGbeta wild - type ( WT ) and CGbeta lacking EntityN - glycosylation at EntityAsn ( 13 ) ( CGbeta - N13 ) showed aggregates in lysate. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | These results indicate that the backbone structure consisting of 114 amino acids and EntityN - linked glycosylation at EntityAsn ( 30 ) is involved in the aggregation of LHbeta. |
| 1.0000 | Methylation | These results indicate that the backbone structure consisting of 114 amino acids and N - linked Entityglycosylation at EntityAsn ( 30 ) is involved in the aggregation of LHbeta. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Moreover, EntityN - glycosylation at EntityAsn ( 13 ) does not prevent such aggregation, but instead plays an important role in correct folding for both LHbeta - and CGbeta - subunits to be secreted as monomer. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Type XIII collagen alpha chains were found to associate into disulfide - bonded trimers, and Entityhydroxylation of Entityproline residues dramatically enhanced this association. |
| 0.9997 | Methylation | Type XIII collagen alpha chains were found to associate into disulfide - bonded trimers, and Entityhydroxylation of Entityproline residues dramatically enhanced this association. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9970 | Methylation | Symmetric and asymmetric EntityDNA methylation in the human IGF2 - H19 Entityimprinted region . |
| 0.9973 | Methylation | Symmetric and asymmetric DNA Entitymethylation in the human IGF2 - H19 Entityimprinted region . |
| 0.9923 | Methylation | Symmetric and asymmetric DNA Entitymethylation in the human IGF2 - H19 Entityimprinted region. |
| 0.9913 | Methylation | Symmetric and asymmetric EntityDNA methylation in the human IGF2 - H19 Entityimprinted region. |
| 0.9487 | Methylation | Symmetric and asymmetric EntityDNA methylation in the human IGF2 - H19 Entityimprinted region . |
| 0.8638 | Methylation | Symmetric and asymmetric EntityDNA methylation in the human IGF2 - H19 Entityimprinted region. |
| 0.6757 | Methylation | Symmetric and asymmetric EntityDNA Entitymethylation in the human IGF2 - H19 imprinted region. |
| 0.6489 | Methylation | Symmetric and asymmetric EntityDNA EntityDNA methylation in the human IGF2 - H19 imprinted region. |
| 0.6317 | Methylation | Symmetric and asymmetric EntityDNA methylation Entitymethylation in the human IGF2 - H19 imprinted region. |
| 0.5755 | Methylation | Symmetric and asymmetric EntityDNA methylation Entitymethylation in the human IGF2 - H19 imprinted region. |
| 0.4911 | Methylation | Symmetric and asymmetric EntityDNA methylation EntityDNA methylation in the human IGF2 - H19 imprinted region. |
| 0.4623 | Methylation | Symmetric and asymmetric EntityDNA Entitymethylation in the human IGF2 - H19 imprinted region. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9981 | Methylation | The presence of a differential Entitymethylation region ( DMR ) on the two parental alleles at the Entity5'flanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.9980 | Methylation | The presence of a differential Entitymethylation region ( DMR ) on the two parental alleles at the Entity5'flanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.9970 | Methylation | The presence of a differential Entitymethylation region ( DMR ) on the two parental alleles at the Entity5 ' flanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.9970 | Methylation | The presence of a differential Entitymethylation region ( DMR ) on the two parental alleles at the 5 ' Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.9968 | Methylation | The presence of a differential Entitymethylation region ( DMR ) on the two parental alleles at the 5 ' Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.5844 | Methylation | The presence of a differential methylation region ( DMR ) on the two parental alleles at the 5 ' Entityflanking Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.5536 | Methylation | The presence of a differential methylation region ( DMR ) on the two parental alleles at the Entity5'flanking region Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.5433 | Methylation | The presence of a differential methylation region ( DMR ) on the two parental alleles at the Entity5'flanking Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.4431 | Methylation | The presence of a differential methylation region ( DMR ) on the two parental alleles at the Entity5 ' Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.4217 | Methylation | The presence of a differential methylation region ( DMR ) on the two parental alleles at the 5 ' Entityflanking region Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.4042 | Methylation | The presence of a differential methylation region ( DMR ) on the two parental alleles at the Entity5'flanking region Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| 0.4023 | Methylation | The presence of a differential methylation region ( DMR ) on the two parental alleles at the Entity5'flanking region Entityflanking region of H19 has been proposed to constitute the gametic imprint, which controls the reciprocal allelic expression of the two genes. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Using bisulfite genomic sequencing, we have assessed the Entitymethylation status of Entitycytosine ( including 154 CpG sites ) in six CpG - rich regions of the human IGF2 - H19 genes. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | In a CpG island near promoter P3 of the IGF2 gene, more than 99. 8 % of all cytosines were converted to thymidine by sodium bisulfite mutagenesis, indicating that none of the EntityCpGs was Entitymethylated . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | In the IGF2 exon 8 - 9 region, mosaic Entitymethylation of 56 EntityCpG sites was observed in fetal tissues and in adult blood DNA. |
| 0.9997 | Methylation | In the IGF2 exon 8 - 9 region, mosaic Entitymethylation of 56 EntityCpG sites was observed in fetal tissues and in adult blood DNA. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | In contrast to the mosaic Entitymethylation of EntityIGF2 , the allelic methylation of the human H19 DMR was uniform. |
| 0.9959 | Methylation | In contrast to the mosaic methylation of IGF2, the allelic Entitymethylation of the human H19 EntityDMR was uniform. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | In the CpG region located 2 kb upstream ( - 2362 to - 1911 ) of the H19 transcription site, all Entity25 CpG sites were completely Entitymethylated on only one parental allele. |
| 1.0000 | Methylation | In the CpG region located 2 kb upstream ( - 2362 to - 1911 ) of the H19 transcription site, all 25 EntityCpG sites were completely Entitymethylated on only one parental allele. |
| 0.9982 | Methylation | In the CpG region located 2 kb upstream ( - 2362 to - 1911 ) of the H19 transcription site, all Entity25 CpG sites were completely Entitymethylated on only one parental allele. |
| 0.9975 | Methylation | In the CpG region located 2 kb upstream ( - 2362 to - 1911 ) of the H19 transcription site, all Entity25 CpG sites were completely Entitymethylated on only one parental allele. |
| 0.9974 | Methylation | In the CpG region located 2 kb upstream ( - 2362 to - 1911 ) of the H19 transcription site, all 25 EntityCpG sites were completely Entitymethylated on only one parental allele. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Uniform allele - specific Entitymethylation was also observed in the EntityCpG island proximal to the H19 promoter ( - 711 to - 290 ) with complete methylation of all 25 CpG sites in one parental allele. |
| 0.9999 | Methylation | Uniform allele - specific methylation was also observed in the CpG island proximal to the H19 promoter ( - 711 to - 290 ) with complete Entitymethylation of all 25 EntityCpG sites in one parental allele. |
| 0.9999 | Methylation | Uniform allele - specific methylation was also observed in the CpG island proximal to the H19 promoter ( - 711 to - 290 ) with Entitycomplete methylation of all 25 EntityCpG sites in one parental allele. |
| Methylation | Uniform allele - specific methylation was also observed in the CpG island proximal to the H19 promoter ( - 711 to - 290 ) with complete Entitymethylation of all Entity25 CpG sites in one parental allele. | |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9989 | Methylation | In contrast, the EntityCpG region in the H19 promoter ( - 292 to + 15 ) was mosaically Entitymethylated in all tissues. |
| 0.9930 | Methylation | In contrast, the EntityCpG region in the H19 promoter ( - 292 to + 15 ) was mosaically Entitymethylated in all tissues. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | In addition, cytosine was Entitymethylated at three EntityCpNpG and GpNpC sites on the top DNA strand and one CpNpG site on the bottom DNA strand from the fetal brain. |
| 0.9997 | Methylation | In addition, cytosine was Entitymethylated at three CpNpG and EntityGpNpC sites on the top DNA strand and one CpNpG site on the bottom DNA strand from the fetal brain. |
| 0.9988 | Methylation | In addition, cytosine was Entitymethylated at three CpNpG and GpNpC sites on the top DNA strand and one EntityCpNpG site on the bottom DNA strand from the fetal brain. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9987 | Methylation | The cytosines at CpG sites were methylated on both DNA strands ( symmetric methylation ) while Entitycytosines at the CpNpG and GpNpC sites were Entitymethylated on only one DNA strand ( asymmetric methylation ). |
| 0.9955 | Methylation | The Entitycytosines at CpG sites were Entitymethylated on both DNA strands ( symmetric methylation ) while cytosines at the CpNpG and GpNpC sites were methylated on only one DNA strand ( asymmetric methylation ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9992 | Methylation | The asymmetric Entitymethylation was associated with tissue - specific disruption of EntityH19 genomic imprinting in fetal brain. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9985 | Methylation | An increase in Entityhistone Entityacetylation and IL - 2 antagonizing the immunoinhibitory effect are necessary for augmentation by butyrate of in vitro anti - TNP antibody production. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | We investigated the role of Entityhistone Entityacetylation in the promotion of antigen - specific antibody production in murine B cells induced by sodium butyrate ( NaBu ) plus interleukin 2 ( IL - 2 ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | NaBu dose dependently increased the Entityacetylation levels of Entityhistone H4 at concentrations which effectively enhanced anti - trinitrophenyl ( TNP ) antibody production in the presence of IL - 2. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9980 | Methylation | Among other short - chain fatty acids and NaBu analogs, propionate, valerate and vinylacetate were effective in the presence of IL - 2 in increasing both antibody production and the Entityhistone H4 Entityacetylation level, but acetate, alpha -, beta - and gamma - hydroxybutyrates and alpha -, beta - and gamma - aminobutyrates were not effective, even in the presence of IL - 2. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Splenic B cells treated with NaBu, TSA and both together in the presence or absence of IL - 2 showed almost the same increased Entityacetylation level of Entityhistone H4 . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9989 | Methylation | These results suggest that the NaBu - induced enhancement of anti - TNP antibody production in the presence of IL - 2 is mediated through a moderate increase in the level of Entityhistone Entityacetylation and that NaBu has both stimulating and inhibiting activities for anti - TNP antibody production, the latter of which is overcome by IL - 2. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9994 | Methylation | Evidence that the lizard Entityhelospectin peptides are EntityO - glycosylated . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9980 | Methylation | The Entityglycosylation did not affect the capacity of the Entityhelospectins to recognize and to activate the human and the rat VPAC1 and VPAC2 receptors. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Hepatic levels of methionine, SAM, and DNA methylation fell by approximately 40 %. Entityc - myc was Entityhypomethylated , and its mRNA level increased. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Calf histones H2A and H4 and bovine Entitymyelin basic protein were Entitymethylated by Hsl7p, whereas histones H1, H2B, and H3 and bovine cytochrome c were not. |
| 1.0000 | Methylation | Calf histones H2A and H4 and bovine myelin basic protein were Entitymethylated by EntityHsl7p , whereas histones H1, H2B, and H3 and bovine cytochrome c were not. |
| 0.9997 | Methylation | Calf histones H2A and H4 and bovine myelin basic protein were Entitymethylated by Hsl7p, whereas histones H1, EntityH2B , and H3 and bovine cytochrome c were not. |
| 0.9997 | Methylation | Calf histones H2A and H4 and bovine myelin basic protein were Entitymethylated by Hsl7p, whereas Entityhistones H1 , H2B, and H3 and bovine cytochrome c were not. |
| 0.9995 | Methylation | Calf histones H2A and H4 and bovine myelin basic protein were Entitymethylated by Hsl7p, whereas histones H1, H2B, and EntityH3 and bovine cytochrome c were not. |
| 0.9993 | Methylation | Calf histones H2A and EntityH4 and bovine myelin basic protein were Entitymethylated by Hsl7p, whereas histones H1, H2B, and H3 and bovine cytochrome c were not. |
| 0.9992 | Methylation | Calf histones H2A and H4 and bovine myelin basic protein were Entitymethylated by Hsl7p, whereas histones H1, H2B, and H3 and bovine Entitycytochrome c were not. |
| 0.9974 | Methylation | Calf Entityhistones H2A and H4 and bovine myelin basic protein were Entitymethylated by Hsl7p, whereas histones H1, H2B, and H3 and bovine cytochrome c were not. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Rapid induction of Entityhistone Entityhyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase - 1. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9985 | Methylation | EntityHyperacetylated Entityhistone H4 appeared within 2 h of the addition of quinidine to the medium, and levels were maximal by 24 h. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Quinidine - treated MCF - 7 cells showed elevated Entityp21 ( WAF1 ) , Entityhypophosphorylation and suppression of retinoblastoma protein, and down - regulation of cyclin D1, similar to the cell cycle response observed with cells induced to differentiate by histone deacetylase inhibitors, trichostatin A, and trapoxin. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9921 | Methylation | Thus, Entityoligosaccharides Entityattached to the minK subunit affect not only the gating properties, but also the pH sensitivity of I ( sK ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | A novel post - translational modification of yeast elongation factor 1A. EntityMethylesterification at the C Entityterminus . |
| 1.0000 | Methylation | A novel post - translational modification of yeast elongation factor 1A. EntityMethylesterification at the C Entityterminus. |
| 0.9999 | Methylation | A novel post - translational modification of yeast elongation factor 1A. EntityMethylesterification at the C terminus Entity. |
| Methylation | A novel post - translational modification of yeast elongation factor 1A. Methylesterification Entityat the C Entityterminus. | |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Previous studies have shown that eEF1A is Entitymethylated on several internal Entitylysine residues to give mono -, di -, and tri - N - epsilon - methyl - lysine derivatives. |
| 0.9996 | Methylation | Previous studies have shown that eEF1A is Entitymethylated on several internal Entitylysine residues to give mono -, di -, and tri - N - epsilon - methyl - lysine derivatives. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | In cycloheximide - treated cells, Entitymethyl esterified EntityeEF1A was detected largely in the ribosome and polysome fractions ; little or no methylated protein was found in the soluble fraction. |
| 0.9992 | Methylation | In cycloheximide - treated cells, methyl esterified EntityeEF1A was detected largely in the ribosome and polysome fractions ; little or no Entitymethylated protein was found in the soluble fraction. |
| 0.9999 | Methylation | In cycloheximide - treated cells, methyl Entityesterified EntityeEF1A was detected largely in the ribosome and polysome fractions ; little or no methylated protein was found in the soluble fraction. |
| 0.9999 | Methylation | In cycloheximide - treated cells, Entitymethyl esterified EntityeEF1A was detected largely in the ribosome and polysome fractions ; little or no methylated protein was found in the soluble fraction. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9979 | Methylation | From the results of pulse - chase experiments using radiolabeled intact yeast cells, we find that the EntityN - methylated Entitylysine residues of eEF1A are stable over 4 h, whereas the eEF1A carboxyl methyl ester has a half - life of less than 10 min. |
| 0.9982 | Methylation | From the results of pulse - chase experiments using radiolabeled intact yeast cells, we find that the EntityN - methylated Entitylysine residues of eEF1A are stable over 4 h, whereas the eEF1A carboxyl methyl ester has a half - life of less than 10 min. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9987 | Methylation | The rapid turnover of the methyl ester suggests that the Entitymethylation / demethylation of eEF1A at the EntityC - terminal carboxyl group may represent a novel mode of regulation of the activity of this protein in yeast. |
| 0.9988 | Methylation | The rapid turnover of the methyl ester suggests that the Entitymethylation / demethylation of eEF1A at the EntityC - terminal carboxyl group may represent a novel mode of regulation of the activity of this protein in yeast. |
| 0.9987 | Methylation | The rapid turnover of the methyl ester suggests that the Entitymethylation / demethylation of eEF1A at the EntityC - terminal carboxyl group may represent a novel mode of regulation of the activity of this protein in yeast. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Post - translational Entityhydroxylation at the EntityN - terminus of the prion protein reveals presence of PPII structure in vivo. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Almost complete Entityconversion of proline to 4 - hydroxyproline occurs specifically at residue EntityPro44 of this murine protein ; the same hydroxylated residue was detected, at lower levels, in PrP ( Sc ) from the brains of scrapie - infected mice. |
| 0.9960 | Methylation | Almost complete conversion of proline to 4 - hydroxyproline occurs specifically at residue EntityPro44 of this murine protein ; the same Entityhydroxylated residue was detected, at lower levels, in PrP ( Sc ) from the brains of scrapie - infected mice. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Cation binding and / or post - translational Entityhydroxylation of this region of EntityPrP may regulate its role in the physiology and pathobiology of the cell. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9751 | Methylation | Furthermore, loss of Entitymethylation also greatly reduced the association of another yeast B - type subunit, EntityRts1p . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Thus, Entitymethylation of EntityPph21p is important for formation of PP2A trimeric and dimeric complexes, and consequently, for PP2A function. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | E - cadherin expression is silenced by Entity5'CpG island Entitymethylation in acute leukemia. |
| 0.9994 | Methylation | E - cadherin expression is silenced by 5 ' EntityCpG island Entitymethylation in acute leukemia. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | In this study, we used a nested - PCR approach to examine the Entitymethylation status of the E - cadherin Entity5'CpG island in blood and bone marrow samples from normal donors and in bone marrow from patients with acute leukemia. |
| 0.9988 | Methylation | In this study, we used a nested - PCR approach to examine the Entitymethylation status of the E - cadherin 5 ' EntityCpG island in blood and bone marrow samples from normal donors and in bone marrow from patients with acute leukemia. |
| 0.9984 | Methylation | In this study, we used a nested - PCR approach to examine the Entitymethylation status of the E - cadherin 5 ' EntityCpG island in blood and bone marrow samples from normal donors and in bone marrow from patients with acute leukemia. |
| 0.9968 | Methylation | In this study, we used a nested - PCR approach to examine the Entitymethylation status of the E - cadherin Entity5'CpG island in blood and bone marrow samples from normal donors and in bone marrow from patients with acute leukemia. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | In normal peripheral blood mononuclear cells and bone marrow, EntityE - cadherin was completely Entityunmethylated . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | In contrast, EntityE - cadherin was aberrantly Entitymethylated in 4 of 4 ( 100 % ) leukemia cell lines, 14 of 44 ( 32 % ) acute myelogenous leukemias, and 18 of 33 ( 53 % ) acute lymphoblastic leukemias. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Genomic bisulfite sequencing of primary leukemias confirmed dense Entitymethylation across the EntityCpG island . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | EntityMethylation was associated with loss of EntityE - cadherin RNA and protein in leukemia cell lines and primary leukemias. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Following treatment with 5 - aza - 2'- deoxycytidine, a Entitymethylated leukemia cell line expressed both EntityE - cadherin transcript and protein. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Our results show that Entitymethylation of EntityE - cadherin occurs commonly in acute leukemia and suggests a hypothesis for E - cadherin down - regulation in leukemogenesis. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | EntityHypoglycosylated forms of Entityalpha1 - antitrypsin have been detected by Western blot in serum from CDG Ia patients. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | In contrast we were not able to detect Entityhypoglycosylation in Entityalpha1 - antitrypsin synthesized by fibroblasts, keratinocytes, enterocytes, and leukocytes. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9995 | Methylation | Similarly no Entityhypoglycosylation was detectable in a membrane - associated N - linked glycoprotein, the facilitative glucose transporter EntityGLUT - 1 and also in serum immunoglobulin G isolated from sera of CDG Ia patients. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | EntityChM1L protein was expressed on the cell surface as EntityN - glycosylated and non - N - glycosylated protein with molecular mass of 45 and 40 kDa, respectively. |
| 0.9987 | Methylation | EntityChM1L protein was expressed on the cell surface as N - glycosylated and Entitynon - N - glycosylated protein with molecular mass of 45 and 40 kDa, respectively. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.8783 | Methylation | In oxygenated and iron replete cells, HIF - alpha subunits are rapidly destroyed by a mechanism that involves Entityubiquitylation by the von EntityHippel - Lindau tumor suppressor ( pVHL ) E3 ligase complex. |
| 0.6192 | Methylation | In oxygenated and iron replete cells, HIF - alpha subunits are rapidly destroyed by a mechanism that involves Entityubiquitylation by the Entityvon Hippel - Lindau tumor suppressor ( pVHL ) E3 ligase complex. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9980 | Methylation | Here we show that the interaction between human pVHL and a specific domain of the HIF - 1alpha subunit is regulated through Entityhydroxylation of a proline residue ( HIF - 1alpha EntityP564 ) by an enzyme we have termed HIF - alpha prolyl - hydroxylase ( HIF - PH ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9979 | Methylation | We analyzed 100 sporadic and 3 hereditary pancreatic ductal adenocarcinomas for MSI, and high - frequency MSI ( MSI - H ) and low - frequency MSI ( MSI - L ) tumors were further analyzed for frameshift mutations of possible target genes and for Entitypromoter Entitymethylation and mutation of DNA MMR genes, including hMLH1, hMSH2, hMSH3, and hMSH6 genes. |
| 0.9610 | Methylation | We analyzed 100 sporadic and 3 hereditary pancreatic ductal adenocarcinomas for MSI, and high - frequency MSI ( MSI - H ) and low - frequency MSI ( MSI - L ) tumors were further analyzed for frameshift mutations of possible target genes and for Entitypromoter Entitypromoter methylation and mutation of DNA MMR genes, including hMLH1, hMSH2, hMSH3, and hMSH6 genes. |
| 0.8969 | Methylation | We analyzed 100 sporadic and 3 hereditary pancreatic ductal adenocarcinomas for MSI, and high - frequency MSI ( MSI - H ) and low - frequency MSI ( MSI - L ) tumors were further analyzed for frameshift mutations of possible target genes and for Entitypromoter methylation Entitymethylation and mutation of DNA MMR genes, including hMLH1, hMSH2, hMSH3, and hMSH6 genes. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9977 | Methylation | EntityHypermethylation of the hMLH1 Entitypromoter was observed in 6 ( 46 % ) of the 13 sporadic MSI - H tumors but not in any of the 3 hereditary MSI - H tumors or 13 MSI - L tumors. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Synergism of Xist RNA, DNA methylation, and Entityhistone Entityhypoacetylation in maintaining X chromosome inactivation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Xist RNA expression, methylation of CpG islands, and Entityhypoacetylation of Entityhistone H4 are distinguishing features of inactive X chromatin. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Demethylation of DNA, using 5 - azadC or by introducing a mutation in Dnmt1, and inhibition of Entityhistone Entityhypoacetylation using trichostatin A further increases reactivation in Xist mutant fibroblasts, indicating a synergistic interaction of X chromosome silencing mechanisms. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9972 | Methylation | Expression of Pichia anomala EntityINV1 gene in Saccharomyces cerevisiae results in two different active forms of Entityhypoglycosylated invertase. |
| 0.9017 | Methylation | Expression of Pichia anomala EntityINV1 gene in Saccharomyces cerevisiae results in two different active forms of Entityhypoglycosylated invertase . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9994 | Methylation | Two forms of multimeric active and Entityglycosylated Entityinvertase displaying different subcellular locations and molecular masses could be detected in the transformants. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9988 | Methylation | The Entityhypoglycosylated Entityinvertase accumulated within the cells of the transformants to an unusual level ( up to 130 units / 10 ( 10 ) cells ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Such accumulation of active enzyme inside the cells, as well as its Entityunderglycosylation , could be due to intrinsic properties of the P. anomala Entityinvertase that are determined by the particular primary structure of its protein moiety. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | The histone acetyltransferase, hGCN5, interacts with and Entityacetylates the HIV transactivator, EntityTat . |
| 0.9996 | Methylation | The histone acetyltransferase, EntityhGCN5 , interacts with and Entityacetylates the HIV transactivator, Tat. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Here we report that hGCN5, a well known histone acetyltransferase, specifically interacts with and Entityacetylates the human immunodeficiency virus type 1 ( HIV - 1 ) transactivator protein, EntityTat . |
| 0.9976 | Methylation | Here we report that EntityhGCN5 , a well known histone acetyltransferase, specifically interacts with and Entityacetylates the human immunodeficiency virus type 1 ( HIV - 1 ) transactivator protein, Tat. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Tat lysines 50 and Entity51 , target of Entityacetylation by p300 / CBP, were also found to be acetylated by hGCN5. |
| 0.9998 | Methylation | Tat lysines 50 and 51, target of acetylation by p300 / CBP, were also found to be Entityacetylated by EntityhGCN5 . |
| 0.9980 | Methylation | Tat lysines 50 and Entity51 , target of acetylation by p300 / CBP, were also found to be Entityacetylated by hGCN5. |
| 0.9974 | Methylation | Tat Entitylysines 50 and 51, target of Entityacetylation by p300 / CBP, were also found to be acetylated by hGCN5. |
| 0.9837 | Methylation | Tat Entitylysines 50 and 51, target of acetylation by p300 / CBP, were also found to be Entityacetylated by hGCN5. |
| 0.9991 | Methylation | Tat lysines Entity50 and 51, target of Entityacetylation by p300 / CBP, were also found to be acetylated by hGCN5. |
| 0.9942 | Methylation | Tat lysines Entity50 and 51, target of acetylation by p300 / CBP, were also found to be Entityacetylated by hGCN5. |
| 0.9893 | Methylation | Tat Entitylysines 50 and 51, target of Entityacetylation by p300 / CBP, were also found to be acetylated by hGCN5. |
| 0.9396 | Methylation | Tat Entitylysines 50 and 51, target of acetylation by p300 / CBP, were also found to be Entityacetylated by hGCN5. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | The Entityacetylation of these two Entitylysines by p300 / CBP has been recently shown to stimulate Tat transcriptional activity and accordingly, we have found that hGCN5 can considerably enhance Tat - dependent transcription of the HIV - 1 long terminal repeat. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | These data highlight the importance of the Entityacetylation of Entitylysines 50 and 51 in the function of Tat, since different histone acetyltransferases involved in distinct signaling pathways, GCN5 and p300 / CBP, converge to acetylate Tat on the same site. |
| 0.9989 | Methylation | These data highlight the importance of the acetylation of lysines 50 and 51 in the function of Tat, since different histone acetyltransferases involved in distinct signaling pathways, EntityGCN5 and p300 / CBP, converge to Entityacetylate Tat on the same site. |
| 0.9986 | Methylation | These data highlight the importance of the acetylation of lysines 50 and Entity51 in the function of Tat, since different histone acetyltransferases involved in distinct signaling pathways, GCN5 and p300 / CBP, converge to Entityacetylate Tat on the same site. |
| 0.9957 | Methylation | These data highlight the importance of the Entityacetylation of lysines 50 and Entity51 in the function of Tat, since different histone acetyltransferases involved in distinct signaling pathways, GCN5 and p300 / CBP, converge to acetylate Tat on the same site. |
| 0.9925 | Methylation | These data highlight the importance of the acetylation of Entitylysines 50 and 51 in the function of Tat, since different histone acetyltransferases involved in distinct signaling pathways, GCN5 and p300 / CBP, converge to Entityacetylate Tat on the same site. |
| 0.9998 | Methylation | These data highlight the importance of the Entityacetylation of Entitylysines 50 and 51 in the function of Tat, since different histone acetyltransferases involved in distinct signaling pathways, GCN5 and p300 / CBP, converge to acetylate Tat on the same site. |
| 0.9657 | Methylation | These data highlight the importance of the acetylation of Entitylysines 50 and 51 in the function of Tat, since different histone acetyltransferases involved in distinct signaling pathways, GCN5 and p300 / CBP, converge to Entityacetylate Tat on the same site. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Furthermore, a - chains were Entityoverhydroxylated and the ratio of Entityalpha1 ( I ) : alpha2 ( I ) was 3. 2 : 1, consistent with the presence of alpha1 ( I ) homotrimers. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | Linking global Entityhistone Entityacetylation to the transcription enhancement of X - chromosomal genes in Drosophila males. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | It has become well established for several genes that targeting of Entityhistone Entityacetylation to promoters is required for the activation of transcription. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | In Drosophila, a specific modification of H4, Entityacetylation at Entitylysine 16 , is enriched at hundreds of sites on the male X chromosome due to the activity of the male - specific lethal ( MSL ) dosage compensation complex. |
| 0.9985 | Methylation | In Drosophila, a specific modification of H4, Entityacetylation at Entitylysine 16, is enriched at hundreds of sites on the male X chromosome due to the activity of the male - specific lethal ( MSL ) dosage compensation complex. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Utilizing chromatin immunoprecipitation, we have determined that EntityH4Ac16 is present along the entire length of X - linked genes targeted by the MSL complex with relatively modest levels of Entityacetylation at the promoter regions and high levels in the middle and / or 3'end of the transcription units. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | EntityMethylation of Entityhistones at specific residues plays an important role in transcriptional regulation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9308 | Methylation | Chromatin immunoprecipitation of dimethylated lysine 9 on histone H3 across 53 kilobases of the chicken beta - globin locus during erythropoiesis shows an almost complete anticorrelation between regions of elevated Entitylysine 9 Entitymethylation and acetylation. |
| 0.9222 | Methylation | Chromatin immunoprecipitation of dimethylated lysine 9 on Entityhistone H3 across 53 kilobases of the chicken beta - globin locus during erythropoiesis shows an almost complete anticorrelation between regions of elevated lysine 9 methylation and Entityacetylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Methylation | The amino - terminal ectodomain of the human TSH receptor has been expressed at the surface of CHO cells as a Entityglycosylphosphatidylinositol - anchored Entityglycosylphosphatidylinositol - anchored molecule containing a 10 - residue histidine tag close to its C terminus. | |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | This allowed the identification of four out of the six potential EntityN - glycosylation sites as being effectively Entityglycosylated . |
| 0.9992 | Methylation | This allowed the identification of four out of the six potential EntityN - glycosylation sites as being effectively Entityglycosylated . |
| 0.4461 | Methylation | This allowed the identification of four out of the six potential EntityN - glycosylation sites EntityN - glycosylation sites as being effectively glycosylated. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9980 | Methylation | HIF - 1alpha binding to VHL is regulated by stimulus - sensitive Entityproline Entityhydroxylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Through a combination of in vivo coimmunoprecipitation assays using VHL and a panel of point mutants of HIF - 1alpha in this region, as well as MS and in vitro binding assays, we now provide evidence that this modification, which occurs under normoxic conditions, is Entityhydroxylation of EntityPro - 564 of HIF - 1alpha. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | EntityN - glycosylation of EntityCRF receptor type 1 is important for its ligand - specific interaction. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9529 | Methylation | In vitro expression studies showed an influence of EntityN - linked glycosylation Entityglycosylation on expression efficiency, instability, and / or secretion of the mutated proteins. |
| 0.9435 | Methylation | In vitro expression studies showed an influence of EntityN - linked glycosylation Entityglycosylation on expression efficiency, instability, and / or secretion of the mutated proteins. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | These results show that EntityN - linked glycosylation can limit the antibody response to the HCV EntityE1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| 1.0000 | Methylation | These results show that N - linked Entityglycosylation can limit the antibody response to the HCV EntityE1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| 0.9965 | Methylation | These results show that EntityN - linked glycosylation can limit the antibody response to the HCV EntityE1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| 0.8548 | Methylation | These results show that EntityN - linked glycosylation Entityglycosylation can limit the antibody response to the HCV E1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| 0.8246 | Methylation | These results show that EntityN - linked glycosylation Entityglycosylation can limit the antibody response to the HCV E1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| 0.7682 | Methylation | These results show that EntityN - linked Entityglycosylation can limit the antibody response to the HCV E1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| 0.7531 | Methylation | These results show that EntityN - linked EntityN - linked glycosylation can limit the antibody response to the HCV E1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| 0.6236 | Methylation | These results show that EntityN - linked Entityglycosylation can limit the antibody response to the HCV E1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| 0.5492 | Methylation | These results show that EntityN - linked glycosylation EntityN - linked glycosylation can limit the antibody response to the HCV E1 protein and reveal a potential vaccine candidate with enhanced immunogenicity. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Methylation | BAH null mice lack measurable BAH protein in several tissues, lack aspartyl beta - hydroxylase activity in liver preparations, and exhibit no Entityhydroxylation of the Entityepidermal growth factor ( EGF ) domain of clotting Factor X. | |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | In this work, Entitybeta - hydroxylation of EntityAsp residues in EGF domains is demonstrated for a soluble form of a Notch ligand, human Jagged - 1. |
| 0.9997 | Methylation | In this work, Entitybeta - hydroxylation of EntityAsp residues in EGF domains is demonstrated for a soluble form of a Notch ligand, human Jagged - 1. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | Since ESET possesses evolutionarily conserved SET, preSET, and postSET domains implicated in Entityhistone Entitymethylation , we tested the ability of ESET to methylate core histones. |
| 0.9999 | Methylation | Since ESET possesses evolutionarily conserved SET, preSET, and postSET domains implicated in histone methylation, we tested the ability of ESET to Entitymethylate core Entityhistones . |
| 0.7511 | Methylation | Since ESET possesses evolutionarily conserved SET, preSET, and postSET domains implicated in histone methylation, we tested the ability of EntityESET to Entitymethylate core histones. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9886 | Methylation | Together, these findings raise the possibility that transcription factor ERG may participate in transcriptional regulation through EntityESET - mediated histone Entitymethylation . |
| 0.5660 | Methylation | Together, these findings raise the possibility that transcription factor ERG may participate in transcriptional regulation through EntityESET - mediated histone EntityESET - mediated histone methylation. |
| 0.5367 | Methylation | Together, these findings raise the possibility that transcription factor ERG may participate in transcriptional regulation through EntityESET - mediated EntityESET - mediated histone methylation. |
| Methylation | Together, these findings raise the possibility that transcription factor ERG may participate in transcriptional regulation through ESET - mediated Entityhistone Entitymethylation . | |
| Methylation | Together, these findings raise the possibility that transcription factor ERG may participate in transcriptional regulation through EntityESET - mediated EntityESET - mediated histone methylation. | |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | It has recently been shown that HIF - alpha undergoes an iron - and oxygen - dependent modification before it can interact with pVHL, and that this results in Entityhydroxylation of at least one Entityprolyl residue ( HIF - 1alpha, Pro 564 ). |
| 0.9998 | Methylation | It has recently been shown that HIF - alpha undergoes an iron - and oxygen - dependent modification before it can interact with pVHL, and that this results in Entityhydroxylation of at least one Entityprolyl residue ( HIF - 1alpha, Pro 564 ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9993 | Methylation | EntityPromoter Entitymethylation status of the DNA repair genes hMLH1 and MGMT in gastric carcinoma and metaplastic mucosa. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9956 | Methylation | DNA repair genes human Mut L homologue 1 ( hMLH1 ) and EntityO ( 6 ) - methylguanine - DNA methyltransferase ( MGMT ) have been shown to be Entityhypermethylated in certain carcinomas. |
| 0.9864 | Methylation | DNA repair genes human EntityMut L homologue 1 ( hMLH1 ) and O ( 6 ) - methylguanine - DNA methyltransferase ( MGMT ) have been shown to be Entityhypermethylated in certain carcinomas. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | We studied EntityDNA methylation of EntityCpG islands in hMLH1 and MGMT in 50 gastric carcinomas and 10 intestinal metaplastic mucosa samples. |
| 1.0000 | Methylation | We studied DNA Entitymethylation of EntityCpG islands in hMLH1 and MGMT in 50 gastric carcinomas and 10 intestinal metaplastic mucosa samples. |
| 0.9745 | Methylation | We studied EntityDNA methylation of EntityCpG islands in hMLH1 and MGMT in 50 gastric carcinomas and 10 intestinal metaplastic mucosa samples. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | We analyzed the Entitymethylation status of EntityhMLH1 and MGMT using methylation - specific polymerase chain reaction and DNA sequencing analysis. |
| 0.9998 | Methylation | We analyzed the Entitymethylation status of hMLH1 and EntityMGMT using methylation - specific polymerase chain reaction and DNA sequencing analysis. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9906 | Methylation | EntityCpG island Entityhypermethylation of hMLH1 and MGMT was detected in 11 ( 22 % ) and 8 ( 16 % ) of the 50 gastric tumors, respectively. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9989 | Methylation | EntityHypermethylation of the Entitypromoter was more common in intestinal - type gastric carcinomas than in poorly diffuse - type gastric carcinomas ( p = 0. 016 and 0. 021, respectively ; Fisher's exact test ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9955 | Methylation | However, hMLH1 Entitypromoter Entityhypermethylation did not coincide with MGMT promoter hypermethylation except in 1 patient. |
| 0.9932 | Methylation | However, hMLH1 promoter hypermethylation did not coincide with MGMT Entitypromoter Entityhypermethylation except in 1 patient. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9976 | Methylation | EntityHypermethylation of the hMLH1 Entitypromoter but not the MGMT promoter occurred in intestinal metaplastic mucosae. |
| 0.9921 | Methylation | EntityHypermethylation of the hMLH1 promoter but not the MGMT Entitypromoter occurred in intestinal metaplastic mucosae. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9972 | Methylation | Tumor - specific Entitypromoter Entityhypermethylation of hMLH1 may be an early event in carcinogenesis in the stomach. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Together, histone acetyltransferases and histone deacetylases ( HDACs ) determine the Entityacetylation status of Entityhistones . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | We found that the Entityalpha ( 1B ) - AR undergoes EntityN - linked glycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| 0.9999 | Methylation | We found that the Entityalpha ( 1B ) - AR undergoes EntityN - linked glycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| 0.9997 | Methylation | We found that the Entityalpha ( 1B ) - AR undergoes N - linked Entityglycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| 0.8658 | Methylation | We found that the alpha ( 1B ) - AR undergoes EntityN - linked glycosylation Entityglycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| 0.8465 | Methylation | We found that the alpha ( 1B ) - AR undergoes EntityN - linked glycosylation Entityglycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| 0.8410 | Methylation | We found that the alpha ( 1B ) - AR undergoes EntityN - linked Entityglycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| 0.8319 | Methylation | We found that the alpha ( 1B ) - AR undergoes EntityN - linked EntityN - linked glycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| 0.5566 | Methylation | We found that the alpha ( 1B ) - AR undergoes EntityN - linked glycosylation EntityN - linked glycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| 0.5341 | Methylation | We found that the alpha ( 1B ) - AR undergoes EntityN - linked Entityglycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Pulse - chase labeling experiments in BHK - 21 cells demonstrate that the Entityalpha ( 1B ) - AR is synthesized as a 70 kDa core Entityglycosylated precursor that is converted to the 90 kDa mature form of the receptor with a half - time of approximately 2 h. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9977 | Methylation | N - Linked Entityglycosylation of the alpha ( 1B ) - AR occurs at Entityfour asparagines on the N - terminus of the receptor. |
| 0.9988 | Methylation | N - Linked Entityglycosylation of the alpha ( 1B ) - AR occurs at four Entityasparagines on the N - terminus of the receptor. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or EntityO - linked glycosylation , contribute to the structural heterogeneity of the Entityalpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.9993 | Methylation | Our findings demonstrate that EntityN - linked glycosylation and phosphorylation, but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the Entityalpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.9977 | Methylation | Our findings demonstrate that N - linked glycosylation and Entityphosphorylation , but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the Entityalpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 1.0000 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or O - linked Entityglycosylation , contribute to the structural heterogeneity of the Entityalpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.9999 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or EntityO - linked glycosylation, contribute to the structural heterogeneity of the Entityalpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.9993 | Methylation | Our findings demonstrate that N - linked Entityglycosylation and phosphorylation, but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the Entityalpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.9981 | Methylation | Our findings demonstrate that EntityN - linked glycosylation and phosphorylation, but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the Entityalpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.7844 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or EntityO - linked glycosylation Entityglycosylation , contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.6685 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or EntityO - linked glycosylation Entityglycosylation , contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.6467 | Methylation | Our findings demonstrate that EntityN - linked glycosylation Entityglycosylation and phosphorylation, but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.5924 | Methylation | Our findings demonstrate that EntityN - linked glycosylation Entityglycosylation and phosphorylation, but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.5883 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or EntityO - linked Entityglycosylation , contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.5019 | Methylation | Our findings demonstrate that EntityN - linked EntityN - linked glycosylation and phosphorylation, but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.4980 | Methylation | Our findings demonstrate that EntityN - linked Entityglycosylation and phosphorylation, but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.4769 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or EntityO - linked EntityO - linked glycosylation , contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.4698 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or EntityO - linked glycosylation EntityO - linked glycosylation, contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.4490 | Methylation | Our findings demonstrate that N - linked glycosylation and phosphorylation, but not palmitoylation or EntityO - linked Entityglycosylation , contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| 0.4099 | Methylation | Our findings demonstrate that EntityN - linked Entityglycosylation and phosphorylation, but not palmitoylation or O - linked glycosylation, contribute to the structural heterogeneity of the alpha ( 1B ) - AR as it is observed in SDS - PAGE. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Our findings indicate that the Semliki Forest virus system can provide large amounts of functional and fully Entityglycosylated Entityalpha ( 1B ) - AR protein suitable for biochemical and structural studies. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Binding mode analysis of 3 - ( 4 - benzoyl - 1 - methyl - 1H - 2 - pyrrolyl ) - N - hydroxy - 2 - propenamide : a new synthetic histone deacetylase inhibitor inducing Entityhistone Entityhyperacetylation , growth inhibition, and terminal cell differentiation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Similarly, 1a - c are endowed with anti - HDAC activity in vivo : on mouse A20 cells, 1a - c induced histone hyperacetylation leading to a highly increased Entityacetylation level of EntityH4 as compared to control histones. |
| 0.9979 | Methylation | Similarly, 1a - c are endowed with anti - HDAC activity in vivo : on mouse A20 cells, 1a - c induced Entityhistone Entityhyperacetylation leading to a highly increased acetylation level of H4 as compared to control histones. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | The edge was methylated in 11 of 22 primary gastric cancers, whereas the Entitycenter was not Entitymethylated in any cancer. |
| 0.9993 | Methylation | The Entityedge was Entitymethylated in 11 of 22 primary gastric cancers, whereas the center was not methylated in any cancer. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9993 | Methylation | EntityINSIG1 expression was markedly reduced in 19 cancers, including the 11 cancers with the Entitymethylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | By 5 - aza - 2'- deoxycytidine treatment of 5 cell lines with the Entitymethylation of the Entityedge , partial restoration of INSIG1 expression was detected only in 2 of them. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | These data indicated that, although the reduced INSIG1 expression in cancers was associated with the Entitymethylation at the Entityedge of the CGI in the promoter region, the methylation was likely to be a secondary change. |
| 0.9960 | Methylation | These data indicated that, although the reduced INSIG1 expression in cancers was associated with the Entitymethylation at the edge of the EntityCGI in the promoter region, the methylation was likely to be a secondary change. |
| 0.7434 | Methylation | These data indicated that, although the reduced INSIG1 expression in cancers was associated with the methylation at the Entityedge of the CGI in the promoter region, the Entitymethylation was likely to be a secondary change. |
| 0.6073 | Methylation | These data indicated that, although the reduced INSIG1 expression in cancers was associated with the methylation at the edge of the EntityCGI in the promoter region, the Entitymethylation was likely to be a secondary change. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | As for p41 - Arc, a DNA fragment was derived from a EntityCGI overlapping exon 8 , and its Entitymethylation did not correlate with its expression. |
| 1.0000 | Methylation | As for p41 - Arc, a DNA fragment was derived from a CGI overlapping Entityexon 8 , and its Entitymethylation did not correlate with its expression. |
| 1.0000 | Methylation | As for p41 - Arc, a DNA fragment was derived from a CGI Entityoverlapping exon 8 , and its Entitymethylation did not correlate with its expression. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | However, Entitymethylation of a EntityCGI in the promoter region with a marked reduction of its expression was observed in 1 of the 22 primary cancers. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | The kyphoscoliotic type of Ehlers - Danlos syndrome ( type VI ) : differential effects on the Entityhydroxylation of Entitylysine in collagens I and II revealed by analysis of cross - linked telopeptides from urine. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9986 | Methylation | A cross - linked N - telopeptide fraction that is derived from bone type I collagen contained only LP, no HP, which means that the helical lysines at residues 930 of alpha 1 ( I ) and Entity933 of alpha 2 ( I ) of the collagen triple - helix had not been Entityhydroxylated . |
| 0.9975 | Methylation | A cross - linked N - telopeptide fraction that is derived from bone type I collagen contained only LP, no HP, which means that the helical lysines at Entityresidues 930 of alpha 1 ( I ) and 933 of alpha 2 ( I ) of the collagen triple - helix had not been Entityhydroxylated . |
| 0.9976 | Methylation | A cross - linked N - telopeptide fraction that is derived from bone type I collagen contained only LP, no HP, which means that the helical lysines at residues Entity930 of alpha 1 ( I ) and 933 of alpha 2 ( I ) of the collagen triple - helix had not been Entityhydroxylated . |
| 0.9931 | Methylation | A cross - linked N - telopeptide fraction that is derived from bone type I collagen contained only LP, no HP, which means that the helical Entitylysines at residues 930 of alpha 1 ( I ) and 933 of alpha 2 ( I ) of the collagen triple - helix had not been Entityhydroxylated . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | The results show that in EDS VIA, bone type I collagen is more markedly Entityunderhydroxylated than cartilage Entitytype II collagen , at least at those helical sites that form cross - links. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9965 | Methylation | Postsynthetic Entitytrimethylation of histone H4 at Entitylysine 20 in mammalian tissues is associated with aging. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9995 | Methylation | EntityMethylation of the EntityN - terminal region of histones was first described more than 35 years ago, but its biological significance has remained unclear. |
| 0.9994 | Methylation | EntityMethylation of the EntityN - terminal region of histones was first described more than 35 years ago, but its biological significance has remained unclear. |
| 0.5032 | Methylation | Methylation of the EntityN - terminal EntityN - terminal region of histones was first described more than 35 years ago, but its biological significance has remained unclear. |
| 0.4565 | Methylation | Methylation of the EntityN - terminal region EntityN - terminal region of histones was first described more than 35 years ago, but its biological significance has remained unclear. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Primarily because of the recent discovery of the SET domain - depending H3 - specific histone methyltransferases SUV39H1 and EntitySuv39h1 , which selectively Entitymethylate lysine 9 of the H3 N terminus, this posttranslational modification has regained scientific interest. |
| 0.9987 | Methylation | Primarily because of the recent discovery of the SET domain - depending H3 - specific histone methyltransferases EntitySUV39H1 and Suv39h1, which selectively Entitymethylate lysine 9 of the H3 N terminus, this posttranslational modification has regained scientific interest. |
| 0.9927 | Methylation | Primarily because of the recent discovery of the SET domain - depending H3 - specific histone methyltransferases SUV39H1 and Suv39h1, which selectively Entitymethylate Entitylysine 9 of the H3 N terminus, this posttranslational modification has regained scientific interest. |
| 0.9733 | Methylation | Primarily because of the recent discovery of the SET domain - depending H3 - specific histone methyltransferases SUV39H1 and Suv39h1, which selectively Entitymethylate Entitylysine 9 of the H3 N terminus, this posttranslational modification has regained scientific interest. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | In the past, investigations concerning the biological significance of Entityhistone Entitymethylation were largely limited because of a lack of simple and sensitive analytical procedures for detecting this modification. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | The present work investigated the Entitymethylation pattern of Entityhistone H4 both in different mammalian organs of various ages and in cell lines by applying mass spectrometric analysis and a newly developed hydrophilic - interaction liquid chromatographic method enabling the simultaneous separation of methylated and acetylated forms, which obviates the need to work with radioactive materials. |
| 0.7415 | Methylation | The present work investigated the methylation pattern of Entityhistone H4 both in different mammalian organs of various ages and in cell lines by applying mass spectrometric analysis and a newly developed hydrophilic - interaction liquid chromatographic method enabling the simultaneous separation of methylated and Entityacetylated forms, which obviates the need to work with radioactive materials. |
| 0.5063 | Methylation | The present work investigated the methylation pattern of Entityhistone H4 both in different mammalian organs of various ages and in cell lines by applying mass spectrometric analysis and a newly developed hydrophilic - interaction liquid chromatographic method enabling the simultaneous separation of Entitymethylated and acetylated forms, which obviates the need to work with radioactive materials. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9987 | Methylation | In rat kidney and liver the Entitydimethylated Entitylysine 20 was found to be the main methylation product, whereas the monomethyl derivative was present in much smaller amounts. |
| 0.9987 | Methylation | In rat kidney and liver the dimethylated Entitylysine 20 was found to be the main methylation product, whereas the Entitymonomethyl derivative was present in much smaller amounts. |
| 0.9999 | Methylation | In rat kidney and liver the dimethylated Entitylysine 20 was found to be the main Entitymethylation product, whereas the monomethyl derivative was present in much smaller amounts. |
| 0.9964 | Methylation | In rat kidney and liver the dimethylated Entitylysine 20 was found to be the main Entitymethylation product, whereas the monomethyl derivative was present in much smaller amounts. |
| 0.9956 | Methylation | In rat kidney and liver the Entitydimethylated Entitylysine 20 was found to be the main methylation product, whereas the monomethyl derivative was present in much smaller amounts. |
| 0.9810 | Methylation | In rat kidney and liver the dimethylated Entitylysine 20 was found to be the main methylation product, whereas the Entitymonomethyl derivative was present in much smaller amounts. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | In addition, for the first time a Entitytrimethylated form of Entitylysine 20 of H4 was found in mammalian tissue. |
| 0.9992 | Methylation | In addition, for the first time a Entitytrimethylated form of Entitylysine 20 of H4 was found in mammalian tissue. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9995 | Methylation | A significant increase in this trimethylated Entityhistone H4 was detected in organs of animals older than 30 days, whereas the amounts of Entitymono - and dimethylated forms did not essentially change in organs from young ( 10 days old ) or old animals ( 30 and 450 days old ). |
| 0.9994 | Methylation | A significant increase in this Entitytrimethylated Entityhistone H4 was detected in organs of animals older than 30 days, whereas the amounts of mono - and dimethylated forms did not essentially change in organs from young ( 10 days old ) or old animals ( 30 and 450 days old ). |
| 0.9991 | Methylation | A significant increase in this trimethylated Entityhistone H4 was detected in organs of animals older than 30 days, whereas the amounts of mono - and Entitydimethylated forms did not essentially change in organs from young ( 10 days old ) or old animals ( 30 and 450 days old ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | EntityTrimethylated EntityH4 was also detected in transformed cells ; although it was present in only trace amounts in logarithmically growing cells, we found an increase in trimethylated lysine 20 in cells in the stationary phase. |
| 0.9844 | Methylation | Trimethylated H4 was also detected in transformed cells ; although it was present in only trace amounts in logarithmically growing cells, we found an increase in Entitytrimethylated Entitylysine 20 in cells in the stationary phase. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | EntityGlycosylation of human Entityproteinase - activated receptor - 2 ( hPAR2 ) : role in cell surface expression and signalling. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | We have analysed the role of EntityN - linked glycosylation in regulating human Entityproteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| 0.9998 | Methylation | We have analysed the role of N - linked Entityglycosylation in regulating human Entityproteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| 0.9393 | Methylation | We have analysed the role of EntityN - linked glycosylation in regulating human Entityproteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| 0.8599 | Methylation | We have analysed the role of EntityN - linked glycosylation Entityglycosylation in regulating human proteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| 0.8415 | Methylation | We have analysed the role of EntityN - linked glycosylation Entityglycosylation in regulating human proteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| 0.8291 | Methylation | We have analysed the role of EntityN - linked EntityN - linked glycosylation in regulating human proteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| 0.8230 | Methylation | We have analysed the role of EntityN - linked Entityglycosylation in regulating human proteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| 0.6961 | Methylation | We have analysed the role of EntityN - linked Entityglycosylation in regulating human proteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| 0.6738 | Methylation | We have analysed the role of EntityN - linked glycosylation EntityN - linked glycosylation in regulating human proteinase - activated receptor - 2 ( hPAR ( 2 ) ) expression and function. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9993 | Methylation | Western blot analysis of wt - hPAR ( 2 ) showed mature Entitywt - hPAR ( 2 ) to have a molecular mass of 55 - 100 kDa, and 33 - 48 kDa following N - glycosidase F Entitydeglycosylation . |
| 0.9956 | Methylation | Western blot analysis of wt - hPAR ( 2 ) showed mature wt - hPAR ( 2 ) to have a molecular mass of 55 - 100 kDa, and 33 - 48 kDa following EntityN - glycosidase F Entitydeglycosylation . |
| 0.9958 | Methylation | Western blot analysis of wt - hPAR ( 2 ) showed mature wt - hPAR ( 2 ) to have a molecular mass of 55 - 100 kDa, and 33 - 48 kDa following N Entity- glycosidase F Entitydeglycosylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Western blot analysis indicated that both EntityN - linked sites are Entityglycosylated . |
| 0.9979 | Methylation | Western blot analysis indicated that both EntityN - linked sites are Entityglycosylated . |
| 0.4813 | Methylation | Western blot analysis indicated that both EntityN - linked sites EntityN - linked sites are glycosylated. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | We conclude that EntityhPAR ( 2 ) EntityN - linked glycosylation and sialylation regulates receptor expression and / or signalling. |
| 0.9956 | Methylation | We conclude that EntityhPAR ( 2 ) EntityN - linked glycosylation and sialylation regulates receptor expression and / or signalling. |
| 0.9867 | Methylation | We conclude that EntityhPAR ( 2 ) N - linked Entityglycosylation and sialylation regulates receptor expression and / or signalling. |
| 0.9268 | Methylation | We conclude that hPAR ( 2 ) EntityN - linked glycosylation Entityglycosylation and sialylation regulates receptor expression and / or signalling. |
| 0.9242 | Methylation | We conclude that hPAR ( 2 ) EntityN - linked Entityglycosylation and sialylation regulates receptor expression and / or signalling. |
| 0.8991 | Methylation | We conclude that hPAR ( 2 ) EntityN - linked glycosylation Entityglycosylation and sialylation regulates receptor expression and / or signalling. |
| 0.8932 | Methylation | We conclude that hPAR ( 2 ) EntityN - linked EntityN - linked glycosylation and sialylation regulates receptor expression and / or signalling. |
| 0.6459 | Methylation | We conclude that hPAR ( 2 ) EntityN - linked Entityglycosylation and sialylation regulates receptor expression and / or signalling. |
| 0.6401 | Methylation | We conclude that hPAR ( 2 ) EntityN - linked glycosylation EntityN - linked glycosylation and sialylation regulates receptor expression and / or signalling. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9988 | Methylation | Histone H3 lysine 4 methylation is Entitymediated by EntitySet1 and promotes maintenance of active chromatin states in fission yeast. |
| 0.9803 | Methylation | Histone H3 Entitylysine 4 Entitymethylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeast. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9951 | Methylation | EntityMethylation of histone H3 at Entitylysine 4 ( H3 Lys - 4 ) or lysine 9 ( H3 Lys - 9 ) is known to define active and silent chromosomal domains respectively from fission yeast to humans. |
| 0.9914 | Methylation | EntityMethylation of histone H3 at lysine 4 ( H3 Lys - 4 ) or Entitylysine 9 ( H3 Lys - 9 ) is known to define active and silent chromosomal domains respectively from fission yeast to humans. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9993 | Methylation | However, in budding yeast, H3 EntityLys - 4 Entitymethylation is also necessary for silent chromatin assembly at telomeres and ribosomal DNA. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9979 | Methylation | Here we demonstrate that deletion of set1, which encodes a protein containing an RNA recognition motif at its amino terminus and a SET domain at the carboxy terminus, abolishes H3 EntityLys - 4 Entitymethylation in fission yeast. |
| 0.9305 | Methylation | Here we demonstrate that deletion of set1, which encodes a protein containing an RNA recognition motif at its amino terminus and a SET domain at the carboxy terminus, abolishes EntityH3 Lys - 4 Entitymethylation in fission yeast. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9759 | Methylation | Unlike in budding yeast, Set1 - mediated H3 EntityLys - 4 Entitymethylation is not required for heterochromatin assembly at the silent mating - type region and centromeres in fission yeast. |
| 0.6041 | Methylation | Unlike in budding yeast, EntitySet1 - mediated EntitySet1 - mediated H3 Lys - 4 methylation is not required for heterochromatin assembly at the silent mating - type region and centromeres in fission yeast. |
| 0.5512 | Methylation | Unlike in budding yeast, EntitySet1 - mediated H3 EntitySet1 - mediated H3 Lys - 4 methylation is not required for heterochromatin assembly at the silent mating - type region and centromeres in fission yeast. |
| Methylation | Unlike in budding yeast, EntitySet1 - mediated EntitySet1 - mediated H3 Lys - 4 methylation is not required for heterochromatin assembly at the silent mating - type region and centromeres in fission yeast. | |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9973 | Methylation | Our analysis suggests that H3 EntityLys - 4 Entitymethylation is a stable histone modification present throughout the cell cycle, including mitosis. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9946 | Methylation | The loss of H3 EntityLys - 4 Entitymethylation in set1Delta cells is correlated with a decrease in histone H3 acetylation levels, suggesting a mechanistic link between H3 Lys - 4 methylation and acetylation of the H3 tail. |
| 0.9913 | Methylation | The loss of H3 Lys - 4 methylation in set1Delta cells is correlated with a decrease in histone H3 acetylation levels, suggesting a mechanistic link between H3 EntityLys - 4 Entitymethylation and acetylation of the H3 tail. |
| 0.9854 | Methylation | The loss of H3 Lys - 4 methylation in set1Delta cells is correlated with a decrease in histone H3 acetylation levels, suggesting a mechanistic link between H3 Lys - 4 methylation and Entityacetylation of the H3 Entitytail . |
| 0.9851 | Methylation | The loss of H3 Lys - 4 methylation in set1Delta cells is correlated with a decrease in Entityhistone H3 Entityacetylation levels, suggesting a mechanistic link between H3 Lys - 4 methylation and acetylation of the H3 tail. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9987 | Methylation | We suggest that methylation of H3 Lys - 4 primarily acts in the maintenance of transcriptionally poised euchromatic domains, and that this modification is dispensable for heterochromatin formation in fission yeast, which instead utilizes H3 EntityLys - 9 Entitymethylation . |
| 0.9942 | Methylation | We suggest that Entitymethylation of H3 EntityLys - 4 primarily acts in the maintenance of transcriptionally poised euchromatic domains, and that this modification is dispensable for heterochromatin formation in fission yeast, which instead utilizes H3 Lys - 9 methylation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9993 | Methylation | Asparagine - 803 in the C - terminal transactivation domain of human hypoxia - inducible factor ( HIF ) - 1 alpha - subunit is Entityhydroxylated by Entityfactor inhibiting HIF - 1 ( FIH - 1 ) under normoxic conditions causing abrogation of the HIF - 1alpha / p300 interaction. |
| 0.9951 | Methylation | EntityAsparagine - 803 in the C - terminal transactivation domain of human hypoxia - inducible factor ( HIF ) - 1 alpha - subunit is Entityhydroxylated by factor inhibiting HIF - 1 ( FIH - 1 ) under normoxic conditions causing abrogation of the HIF - 1alpha / p300 interaction. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9994 | Methylation | NMR and other analyses of a hydroxylated HIF fragment produced in vitro demonstrate that Entityhydroxylation occurs at the beta - carbon of EntityAsn - 803 and imply production of the threo - isomer, in contrast with other known aspartic acid / asparagine hydroxylases that produce the erythro - isomer. |
| 0.5956 | Methylation | NMR and other analyses of a Entityhydroxylated HIF fragment produced in vitro demonstrate that hydroxylation occurs at the beta - carbon of EntityAsn - 803 and imply production of the threo - isomer, in contrast with other known aspartic acid / asparagine hydroxylases that produce the erythro - isomer. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Control of CBP co - activating activity by Entityarginine Entitymethylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Recently, the KIX domain of CBP has been shown to be Entitymethylated by EntityCARM1 in vitro. |
| 0.9985 | Methylation | Recently, the EntityKIX domain of CBP has been shown to be Entitymethylated by CARM1 in vitro. |
| 0.9883 | Methylation | Recently, the EntityKIX domain of CBP has been shown to be Entitymethylated by CARM1 in vitro. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Here, we report that another domain of CBP is specifically Entitymethylated by EntityCARM1 on conserved arginine residues in vitro and in vivo. |
| 1.0000 | Methylation | Here, we report that another domain of EntityCBP is specifically Entitymethylated by CARM1 on conserved arginine residues in vitro and in vivo. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | We also provide functional evidence that arginine residues Entitymethylated by EntityCARM1 play a critical role in GRIP - 1 - dependent transcriptional activation and in hormone - induced gene activation. |
| 0.9997 | Methylation | We also provide functional evidence that Entityarginine residues Entitymethylated by CARM1 play a critical role in GRIP - 1 - dependent transcriptional activation and in hormone - induced gene activation. |
| 0.9928 | Methylation | We also provide functional evidence that Entityarginine residues Entitymethylated by CARM1 play a critical role in GRIP - 1 - dependent transcriptional activation and in hormone - induced gene activation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9990 | Methylation | Gene - specific targeting of EntityH3K9 Entitymethylation is sufficient for initiating repression in vivo. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | Histone H3 Entitylysine 9 ( H3K9 ) Entitymethylation is an epigenetic signal that is recognized by HP1 and correlates with gene silencing in a variety of organisms. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9989 | Methylation | Discovery of the enzymes that catalyze EntityH3K9 Entitymethylation has identified a second gene - specific function for this modification in transcriptional repression. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | Whether EntityH3K9 Entitymethylation is causative in the initiation and establishment of gene repression or is a byproduct of the process leading to the repressed state remains unknown. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | To investigate the role of HMTs and specifically EntityH3K9 Entitymethylation in gene repression, we have employed engineered zinc - finger transcription factors ( ZFPs ) to target HMT activity to a specific endogenous gene. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | Thus, EntityH3K9 Entitymethylation is a primary signal that is sufficient for initiating a gene repression pathway in vivo. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | These bind to, and activate, co - activator molecules that then Entityacetylate core Entityhistones resulting in elevated gene transcription. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9992 | Methylation | Corticosteroids reverse Entityhistone Entityacetylation at the site of inflammatory gene transcription, either by direct binding of the activated glucocorticoid receptor to NF - kappa B - associated co - activators or by recruitment of histone deacetylases to the activated transcription complex. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Probing the conformational and dynamical effects of EntityO - glycosylation within the Entityimmunodominant region of a MUC1 peptide tumor antigen. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9952 | Methylation | However, in neoplastic breast tissue, the Entityextracellular Entitydomain is under - glycosylated, resulting in the exposure of a highly immunogenic core peptide epitope ( PDTRP in bold above ), as well as in the exposure of normally cryptic core Tn ( GalNAc ), STn ( sialyl alpha2 - 6 GalNAc ) and TF ( Gal beta1 - 3 GalNAc ) carbohydrates. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | The results of these studies show that a type I beta - turn conformation is adopted by residues PDTR within the PDTRP region of the Entityunglycosylated EntityMUC1 sequence. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | The existence of a similar beta - turn within the PDTRP core peptide Entityepitope of the Entityunder - glycosylated cancer - associated MUC1 mucin protein might explain the immunodominance of this region in vivo, as the presence of defined secondary structure within peptide epitope regions has been correlated with increased immunogenicity in other systems. |
| Methylation | The existence of a similar beta - turn within the EntityPDTRP core peptide epitope of the Entityunder - glycosylated cancer - associated MUC1 mucin protein might explain the immunodominance of this region in vivo, as the presence of defined secondary structure within peptide epitope regions has been correlated with increased immunogenicity in other systems. | |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | The significance of these results are discussed in relation to the possible roles that peptide epitope secondary structure and Entityglycosylation state may play in EntityMUC1 tumor immunogenicity. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9968 | Methylation | EntityLysine - 79 of histone H3 is Entityhypomethylated at silenced loci in yeast and mammalian cells : a potential mechanism for position - effect variegation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9994 | Methylation | EntityMethylation of Entitylysine - 79 ( K79 ) within the globular domain of histone H3 by Dot1 methylase is important for transcriptional silencing and for association of the Sir silencing proteins in yeast. |
| 0.9926 | Methylation | EntityMethylation of lysine - 79 ( K79 ) within the globular domain of histone H3 by EntityDot1 methylase is important for transcriptional silencing and for association of the Sir silencing proteins in yeast. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | Here, we show that the level of EntityH3 - K79 Entitymethylation is low at all Sir - dependent silenced loci but not at other transcriptionally repressed regions. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | EntityHypomethylation of EntityH3 - K79 at the telomeric and silent mating - type loci, but not the ribosomal DNA, requires the Sir proteins. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9994 | Methylation | Overexpression of Sir3 concomitantly extends the domain of Sir protein association and EntityH3 - K79 Entityhypomethylation at telomeres. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | In mammalian cells, EntityH3 - K79 Entitymethylation is found at loci that are active for V ( D ) J recombination, but not at recombinationally inactive loci that are heterochromatic. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9989 | Methylation | These results suggest that H3 - K79 methylation is an evolutionarily conserved marker of active chromatin regions, and that silencing proteins block the ability of EntityDot1 to Entitymethylate histone H3. |
| 0.9968 | Methylation | These results suggest that EntityH3 - K79 Entitymethylation is an evolutionarily conserved marker of active chromatin regions, and that silencing proteins block the ability of Dot1 to methylate histone H3. |
| 0.9967 | Methylation | These results suggest that H3 - K79 methylation is an evolutionarily conserved marker of active chromatin regions, and that silencing proteins block the ability of Dot1 to Entitymethylate Entityhistone H3 . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9969 | Methylation | Further, they suggest that Sir proteins preferentially bind chromatin with hypomethylated H3 - K79 and then block EntityH3 - K79 Entitymethylation . |
| 0.9873 | Methylation | Further, they suggest that Sir proteins preferentially bind chromatin with Entityhypomethylated EntityH3 - K79 and then block H3 - K79 methylation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9995 | Methylation | This positive feedback loop, and the reverse loop in which EntityH3 - K79 Entitymethylation weakens Sir protein association and leads to further methylation, suggests a model for position - effect variegation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9987 | Methylation | Cyclosporin A prevents the hypoxic adaptation by activating hypoxia - inducible factor - 1alpha EntityPro - 564 Entityhydroxylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | We conclude that CsA destabilizes HIF - 1alpha by promoting Entityhydroxylation of EntityPro - 564 in the ODD domain. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation ( 5 - aza - 2'- deoxycytidine ) and Entityhistone Entitydeacetylation ( trichostatin A, depsipeptide ) in combination against myeloid leukemic cells. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | During the development of leukemia, genes that suppress growth and induce differentiation can be silenced by aberrant DNA methylation and by changes in chromatin structure that involve Entityhistone Entitydeacetylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | It has been reported that a positive interaction between DNA methylation and Entityhistone Entitydeacetylation takes place to inhibit transcription. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Surprisingly, dystroglycan was cleaved, and Entityalpha dystroglycan was Entityglycosylated with the VIA4 - 1 antigen, in DG ( S654A ) / CT muscles. |
| 1.0000 | Methylation | Surprisingly, dystroglycan was cleaved, and alpha Entitydystroglycan was Entityglycosylated with the VIA4 - 1 antigen, in DG ( S654A ) / CT muscles. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | NgRH1 and EntityNgRH2 were detected on the cell surface of recombinant cell lines as EntityN - glycosylated GPI anchored proteins and, consistent with other GPI anchored proteins, were localized within the lipid rafts of cellular membranes. |
| 0.9995 | Methylation | EntityNgRH1 and NgRH2 were detected on the cell surface of recombinant cell lines as EntityN - glycosylated GPI anchored proteins and, consistent with other GPI anchored proteins, were localized within the lipid rafts of cellular membranes. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Transcriptional elongation by RNA polymerase II and Entityhistone Entitymethylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | In this article, we will review the recent literature linking the key biochemical process of transcriptional elongation by RNA polymerase II to Entityhistone Entitymethylation by COMPASS, Dot1p, and Set2 methyltransferases. |
| 0.9995 | Methylation | In this article, we will review the recent literature linking the key biochemical process of transcriptional elongation by RNA polymerase II to histone Entitymethylation by COMPASS, EntityDot1p , and Set2 methyltransferases. |
| 0.9991 | Methylation | In this article, we will review the recent literature linking the key biochemical process of transcriptional elongation by RNA polymerase II to histone Entitymethylation by COMPASS, Dot1p, and EntitySet2 methyltransferases. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9976 | Methylation | Occurrence of EntityO - linked Xyl - GlcNAc and EntityXyl - Glc disaccharides in trocarin, a factor Xa homolog from snake venom. |
| 0.9955 | Methylation | Occurrence of EntityO - linked EntityXyl - GlcNAc and Xyl - Glc disaccharides in trocarin, a factor Xa homolog from snake venom. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | In this study we show that, in contrast to mammalian EntityXa , which is not Entityglycosylated , trocarin contains an O - linked carbohydrate moiety in its light chain and an N - linked carbohydrate oligosaccharide in its heavy chain. |
| 0.9902 | Methylation | In this study we show that, in contrast to mammalian EntityXa , which is not glycosylated, trocarin contains an EntityO - linked carbohydrate moiety in its light chain and an N - linked carbohydrate oligosaccharide in its heavy chain. |
| 0.9809 | Methylation | In this study we show that, in contrast to mammalian EntityXa , which is not glycosylated, trocarin contains an O - linked carbohydrate moiety in its light chain and an EntityN - linked carbohydrate oligosaccharide in its heavy chain. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.6108 | Methylation | The EntityN - linked Entitycarbohydrate on Asn 45 of the heavy chain is a sialylated, diantennary oligosaccharide that is located at the lip of the active site of the prothrombin activator. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | Here we show that EntityLRP1 is differentially Entityglycosylated in a tissue - specific manner and that carbohydrate addition reduces proteolytic cleavage of the extracellular domain and, concomitantly, ICD release. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | Bone marrow or peripheral blood samples from 48 patients with leukemia were examined by multiplex polymerase chain reaction ( MPCR ) to detect p16 gene homozygous deletion, and restriction enzyme PCR to detect Entityp16 gene Entitymethylation . p16 gene inactivation were detected in 10 of the 48 patients ( 20. 4 % ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9992 | Methylation | They were five patients with p16 homozygous deletion, and five patients with Entityp16 Entitymethylation , respectively. p16 gene inactivation correlates with adverse prognosis features. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | The MENT distribution profile was opposite to that of Entityacetylated core Entityhistones but correlated with that of histone H3 dimethylated at lysine 9 ( H3me2K9 ). |
| 0.9996 | Methylation | The MENT distribution profile was opposite to that of acetylated core histones but correlated with that of histone H3 Entitydimethylated at Entitylysine 9 ( H3me2K9 ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Mutational analysis of MENT and experiments with deacetylase inhibitors revealed the essential role of the reaction center loop domain and an inhibitory affect of Entityhistone Entityhyperacetylation on the MENT - induced chromatin remodeling in vivo. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9995 | Methylation | In vitro, the elimination of the histone H3 N - terminal peptide containing lysine 9 by trypsin blocked chromatin self - association by MENT, while reconstitution with dimethylated but not Entityacetylated EntityN - terminal domain of histone H3 specifically restored chromatin self - association by MENT. |
| 0.9987 | Methylation | In vitro, the elimination of the histone H3 N - terminal peptide containing lysine 9 by trypsin blocked chromatin self - association by MENT, while reconstitution with Entitydimethylated but not acetylated EntityN - terminal domain of histone H3 specifically restored chromatin self - association by MENT. |
| 0.9994 | Methylation | In vitro, the elimination of the histone H3 N - terminal peptide containing lysine 9 by trypsin blocked chromatin self - association by MENT, while reconstitution with dimethylated but not Entityacetylated EntityN - terminal domain of histone H3 specifically restored chromatin self - association by MENT. |
| 0.9985 | Methylation | In vitro, the elimination of the histone H3 N - terminal peptide containing lysine 9 by trypsin blocked chromatin self - association by MENT, while reconstitution with Entitydimethylated but not acetylated EntityN - terminal domain of histone H3 specifically restored chromatin self - association by MENT. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | We suggest that histone H3 modification at lysine 9 directly regulates chromatin condensation by recruiting MENT to chromatin in a fashion that is spatially constrained from active genes by gene boundary elements and Entityhistone Entityhyperacetylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | EntityHistone Entityhyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9997 | Methylation | Herein, we investigated the role of Entityhistone Entitydeacetylation on the mitotic process by inhibiting histone deacetylases shortly before mitosis in human primary fibroblasts. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9992 | Methylation | Cells entering mitosis with Entityhyperacetylated Entityhistones displayed altered chromatin conformation associated with decreased reactivity to the anti - Ser 10 phospho H3 antibody, increased recruitment of protein phosphatase 1 - delta on mitotic chromosomes, and depletion of heterochromatin protein 1 from the centromeric heterochromatin. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | Inhibition of Entityhistone Entitydeacetylation before mitosis produced defective chromosome condensation and impaired mitotic progression in living cells, suggesting that improper chromosome condensation may induce mitotic checkpoint activation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9989 | Methylation | Lagging chromosomes consisting of single or paired sisters were also induced by the presence of Entityhyperacetylated Entityhistones , indicating that the less constrained centromeric organization associated with heterochromatin protein 1 depletion may promote the attachment of kinetochores to microtubules coming from both poles. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | EntityHydroxylated kininogens and Entitykinins . |
| 0.9981 | Methylation | EntityHydroxylated Entitykininogens and kinins. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9989 | Methylation | The present results and our previous results indicate that only Entitykinin moity in H kininogen from human and monkey plasmas has been partially Entityhydroxylated post - translationally by proline - 4 - hydroxylase. |
| 0.4434 | Methylation | The present results and our previous results indicate that only kinin moity in H kininogen from human and monkey plasmas has been partially Entityhydroxylated post - translationally by Entityproline - 4 - hydroxylase . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9995 | Methylation | The EntitySCFs expressed in CHO cells are secreted into the medium in active state and, like the natural SCF, are Entityglycosylated . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9984 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites in HN, which are Entityutilized and presumably account for the escape from neutralization. |
| 0.9991 | Methylation | Some of the deduced amino acid substitutions result in additional N - linked Entityglycosylation sites in HN, which are Entityutilized and presumably account for the escape from neutralization. |
| 0.9970 | Methylation | Some of the deduced amino acid substitutions result in additional N - linked Entityglycosylation sites in HN, which are Entityutilized and presumably account for the escape from neutralization. |
| 0.9945 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites in HN, which are Entityutilized and presumably account for the escape from neutralization. |
| 0.9625 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites in HN, which are Entityutilized and presumably account for the escape from neutralization. |
| 0.8151 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.8138 | Methylation | Some of the deduced amino acid substitutions result in additional N - linked Entityglycosylation sites Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.8119 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.7828 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.7171 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites EntityN - linked glycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.7153 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.7102 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.6894 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.6849 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.6821 | Methylation | Some of the deduced amino acid substitutions result in additional N - linked Entityglycosylation Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.6746 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation sites EntityN - linked glycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.6448 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.5407 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.5377 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation EntityN - linked glycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.5345 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation Entityglycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| 0.4927 | Methylation | Some of the deduced amino acid substitutions result in additional EntityN - linked glycosylation EntityN - linked glycosylation sites in HN, which are utilized and presumably account for the escape from neutralization. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | The influence of EntityN - linked glycosylation on the antigenicity and immunogenicity of rubella virus EntityE1 glycoprotein. |
| 0.9999 | Methylation | The influence of N - linked Entityglycosylation on the antigenicity and immunogenicity of rubella virus EntityE1 glycoprotein. |
| 0.8685 | Methylation | The influence of EntityN - linked glycosylation Entityglycosylation on the antigenicity and immunogenicity of rubella virus E1 glycoprotein. |
| 0.8347 | Methylation | The influence of EntityN - linked glycosylation Entityglycosylation on the antigenicity and immunogenicity of rubella virus E1 glycoprotein. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | The role of EntityN - linked glycosylation on the antigenicity and immunogenicity of EntityE1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| 0.9999 | Methylation | The role of N - linked Entityglycosylation on the antigenicity and immunogenicity of EntityE1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| 0.9783 | Methylation | The role of EntityN - linked glycosylation on the antigenicity and immunogenicity of EntityE1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| 0.8596 | Methylation | The role of EntityN - linked glycosylation Entityglycosylation on the antigenicity and immunogenicity of E1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| 0.7845 | Methylation | The role of EntityN - linked glycosylation Entityglycosylation on the antigenicity and immunogenicity of E1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| 0.7073 | Methylation | The role of EntityN - linked Entityglycosylation on the antigenicity and immunogenicity of E1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| 0.6493 | Methylation | The role of EntityN - linked EntityN - linked glycosylation on the antigenicity and immunogenicity of E1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| 0.6315 | Methylation | The role of EntityN - linked Entityglycosylation on the antigenicity and immunogenicity of E1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| 0.6080 | Methylation | The role of EntityN - linked glycosylation EntityN - linked glycosylation on the antigenicity and immunogenicity of E1 glycoprotein was studied using vaccinia recombinants expressing E1 glycosylation mutants. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | EntityGlycosylation of the Entityinterleukin - 1 receptor type I is required for optimal binding of interleukin - 1. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | To determine the role of Entityglycosylation of the EntityIL - 1 receptor type I ( IL - 1RtI ) in the binding and function of IL - 1, we used four plant lectins and glycosidase treatment on two different T - cell lines ( EL4 - 6. 1 and D10S ) and expressing high number of binding sites for IL - 1. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9923 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the EntityIL - 1RtI is due to N - linked carbohydrates, that the degree of Entityglycosylation can vary in cells of different lineage, and that this N - linked glycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.9541 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the EntityIL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this EntityN - linked glycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.8956 | Methylation | This study demonstrates that Entityglycosylation of the extracellular domain of the IL - 1RtI is due to N - linked Entitycarbohydrates , that the degree of glycosylation can vary in cells of different lineage, and that this N - linked glycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.9473 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the EntityIL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this N - linked Entityglycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.9015 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the EntityIL - 1RtI is due to EntityN - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this N - linked glycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.8832 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the EntityIL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this EntityN - linked glycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.8784 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the IL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this EntityN - linked glycosylation Entityglycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.8477 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the IL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this EntityN - linked glycosylation Entityglycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.7924 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the IL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this EntityN - linked Entityglycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.7901 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the IL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this EntityN - linked EntityN - linked glycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.7245 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the IL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this EntityN - linked Entityglycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| 0.6665 | Methylation | This study demonstrates that glycosylation of the extracellular domain of the IL - 1RtI is due to N - linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this EntityN - linked glycosylation EntityN - linked glycosylation appears to be essential for optimal binding and activity of IL - 1 to its type I receptor. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9986 | Methylation | However, the function of these antigens appears to be dependent on the presence of multiple EntityO - linked Entityalpha - N - acetylgalactosamine ( alpha - GalNAc ) determinants. |
| 0.8171 | Methylation | However, the function of these antigens appears to be dependent on the presence of multiple EntityO - linked Entityalpha - N - acetylgalactosamine ( alpha - GalNAc ) determinants. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | The presence of terminal EntityO - linked Entityalpha - GalNAc determinants on the T. gondii recombinant gp40 was confirmed by reactivity with Helix pomatia lectin and the monoclonal antibody 4E9, which recognizes alpha - GalNAc residues, and digestion with alpha - N - acetylgalactosaminidase. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Aberrant Entitymethylation of EntityDAP - kinase in therapy - related acute myeloid leukemia and myelodysplastic syndromes. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | We studied the Entitymethylation status of EntityDAP - kinase of 194 bone marrow samples from 160 patients with acute myeloid leukemia ( AML ) and 34 with a myelodysplastic syndrome ( MDS ) at the time of initial diagnosis by polymerase chain reaction ( PCR ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | EntityHypermethylation of EntityDAP - kinase was present in 27. 5 % ( 44 of 160 ) of AML and in 47 % ( 16 of 34 ) of MDS specimens and significantly correlated to loss of DAP - kinase expression ( P =. 008 ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | EntityDAP - kinase Entityhypermethylation in AML was associated with myelodysplastic changes in the bone marrow at the time of the initial diagnosis ( P =. 002 ) and with the presence of cytogenetic abnormalities ( P =. 02 ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9941 | Methylation | DNA from paraffin - embedded tissue of 6 APAs was evaluated for microsatellite instability ( MI ), MLH - 1 Entitypromoter Entityhypermethylation , and CTNNB - 1 mutations. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9944 | Methylation | Two tumors exhibited MLH - 1 Entitypromoter Entityhypermethylation and showed focal negative MHL - 1 immunostaining ; 1 of these showed marked architectural complexity and cellular pleomorphism. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9973 | Methylation | Some APAs exhibit MLH - 1 Entitypromoter Entityhypermethylation with focal lack of MLH - 1 immunostaining, a molecular abnormality involved in the transition from complex atypical hyperplasia to endometrioid adenocarcinoma. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9986 | Methylation | A common polymorphism in the oxygen - dependent degradation ( ODD ) domain of hypoxia inducible factor - 1alpha ( HIF - 1alpha ) does not impair EntityPro - 564 Entityhydroxylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Under normoxic conditions, the alpha subunit of HIF is rapidly degraded in a manner dependent on Entityhydroxylation of two conserved Entityproline residues at positions 402 and 564 in HIF - 1alpha in the oxygen - dependent degradation ( ODD ) domain. |
| 0.9999 | Methylation | Under normoxic conditions, the alpha subunit of HIF is rapidly degraded in a manner dependent on Entityhydroxylation of two conserved Entityproline residues at positions 402 and 564 in HIF - 1alpha in the oxygen - dependent degradation ( ODD ) domain. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9975 | Methylation | CONCLUSION : The Pro582Ser change represents a common polymorphism of HIF - 1alpha that does not impair HIF - 1alpha Entityprolyl Entityhydroxylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | When Entitydeglycosylated , the protein displayed the molecular weight expected for the longest EntityCLECSF6 form. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Parental - silenced HeLo1 ( hemizygous for locus 1 ) plants show posttranscriptional silencing of the residing nptII ( neomycin phosphotransferase II ) transgene and cytosine Entitymethylation restricted to the Entity3'end and center part of the transcribed region. |
| 0.9997 | Methylation | Parental - silenced HeLo1 ( hemizygous for locus 1 ) plants show posttranscriptional silencing of the residing nptII ( neomycin phosphotransferase II ) transgene and cytosine Entitymethylation restricted to the 3'end and Entitycenter part of the transcribed region. |
| 0.9999 | Methylation | Parental - silenced HeLo1 ( hemizygous for locus 1 ) plants show posttranscriptional silencing of the residing nptII ( neomycin phosphotransferase II ) transgene and cytosine Entitymethylation restricted to the 3 ' Entityend and center part of the transcribed region. |
| 0.9999 | Methylation | Parental - silenced HeLo1 ( hemizygous for locus 1 ) plants show posttranscriptional silencing of the residing nptII ( neomycin phosphotransferase II ) transgene and cytosine Entitymethylation restricted to the Entity3 ' end and center part of the transcribed region. |
| 0.9997 | Methylation | Parental - silenced HeLo1 ( hemizygous for locus 1 ) plants show posttranscriptional silencing of the residing nptII ( neomycin phosphotransferase II ) transgene and cytosine Entitymethylation restricted to the 3'end and center part of the Entitytranscribed region . |
| 0.9994 | Methylation | Parental - silenced HeLo1 ( hemizygous for locus 1 ) plants show posttranscriptional silencing of the residing nptII ( neomycin phosphotransferase II ) transgene and cytosine Entitymethylation restricted to the 3'end and Entitycenter part of the transcribed region. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | After 24 months of callus in vitro cultivation, an epigenetic variant, designated locus 1E, was obtained in which cytosine Entitymethylation of symmetrical ( CG and CNG ) sites was almost complete within the Entity5'end of the nptII - transcribed region and the 35S promoter. |
| 0.9986 | Methylation | After 24 months of callus in vitro cultivation, an epigenetic variant, designated locus 1E, was obtained in which cytosine Entitymethylation of symmetrical ( CG and CNG ) sites was almost complete within the 5'end of the nptII - transcribed region and the Entity35S promoter . |
| 0.9997 | Methylation | After 24 months of callus in vitro cultivation, an epigenetic variant, designated locus 1E, was obtained in which cytosine Entitymethylation of symmetrical ( CG and CNG ) sites was almost complete within the Entity5 ' end of the nptII - transcribed region and the 35S promoter. |
| 0.9997 | Methylation | After 24 months of callus in vitro cultivation, an epigenetic variant, designated locus 1E, was obtained in which cytosine Entitymethylation of symmetrical ( CG and CNG ) sites was almost complete within the 5 ' Entityend of the nptII - transcribed region and the 35S promoter. |
| 0.9994 | Methylation | After 24 months of callus in vitro cultivation, an epigenetic variant, designated locus 1E, was obtained in which cytosine Entitymethylation of symmetrical ( CG and CNG ) sites was almost complete within the 5'end of the nptII - transcribed Entityregion and the 35S promoter. |
| 0.9990 | Methylation | After 24 months of callus in vitro cultivation, an epigenetic variant, designated locus 1E, was obtained in which cytosine Entitymethylation of symmetrical ( CG and CNG ) sites was almost complete within the 5'end of the nptII - transcribed region and the 35S Entitypromoter . |
| 0.9980 | Methylation | After 24 months of callus in vitro cultivation, an epigenetic variant, designated locus 1E, was obtained in which cytosine Entitymethylation of symmetrical ( CG and CNG ) sites was almost complete within the 5'end of the nptII - transcribed region and the Entity35S promoter. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Further, Entitymethylation of nonsymmetrical sites appeared de novo in the Entitypromoter , whereas this type of methylation was significantly reduced in the 3'end of the transcribed region when compared with locus 1. |
| 0.9981 | Methylation | Further, Entitymethylation of nonsymmetrical sites appeared de novo in the promoter, whereas this type of methylation was significantly reduced in the 3'end of the Entitytranscribed region when compared with locus 1. |
| 0.9993 | Methylation | Further, methylation of nonsymmetrical sites appeared de novo in the promoter, whereas this type of Entitymethylation was significantly reduced in the Entity3 ' end of the transcribed region when compared with locus 1. |
| 0.9987 | Methylation | Further, methylation of nonsymmetrical sites appeared de novo in the promoter, whereas this type of Entitymethylation was significantly reduced in the 3'end of the Entitytranscribed region when compared with locus 1. |
| 0.9978 | Methylation | Further, methylation of nonsymmetrical sites appeared de novo in the promoter, whereas this type of Entitymethylation was significantly reduced in the 3'end of the Entitytranscribed region when compared with locus 1. |
| 0.9967 | Methylation | Further, Entitymethylation of nonsymmetrical sites appeared de novo in the promoter, whereas this type of methylation was significantly reduced in the 3'end of the Entitytranscribed region when compared with locus 1. |
| 0.9966 | Methylation | Further, Entitymethylation of nonsymmetrical sites appeared de novo in the promoter, whereas this type of methylation was significantly reduced in the Entity3 ' end of the transcribed region when compared with locus 1. |
| 0.9929 | Methylation | Further, methylation of nonsymmetrical sites appeared de novo in the Entitypromoter , whereas this type of Entitymethylation was significantly reduced in the 3'end of the transcribed region when compared with locus 1. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9972 | Methylation | The protein and steady - state RNA levels remained low in locus 1E, whereas with nuclear run - on assays, no detectable amounts of primary transcripts were found along the nptII gene, indicating that the Entitymethylated Entitypromoter became inactivated. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Frequent Entitymethylation of Entityp16INK4A and p14ARF genes implicated in the evolution of chronic myeloid leukaemia from its chronic to accelerated phase. |
| 0.9999 | Methylation | Frequent Entitymethylation of p16INK4A and Entityp14ARF genes implicated in the evolution of chronic myeloid leukaemia from its chronic to accelerated phase. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9958 | Methylation | Aberrant Entitymethylation of the p16 ( INK4A ) or p14 ( ARF ) Entitypromoters was found in 14 of 30 AP samples. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | The most common situation was the simultaneous Entitymethylation of both Entitypromoters . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9984 | Methylation | Our data indicate that p16 ( INK4A ) and p14 ( ARF ) are primary targets for inactivation by Entitypromoter Entitymethylation in the acceleration of CML. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | We also show that hSWI / SNF - associated PRMT5 can Entitymethylate hypoacetylated Entityhistones H3 and H4 more efficiently than hyperacetylated histones H3 and H4. |
| 0.9999 | Methylation | We also show that hSWI / SNF - associated PRMT5 can Entitymethylate hypoacetylated histones H3 and EntityH4 more efficiently than hyperacetylated histones H3 and H4. |
| 0.9989 | Methylation | We also show that hSWI / SNF - associated EntityPRMT5 can Entitymethylate hypoacetylated histones H3 and H4 more efficiently than hyperacetylated histones H3 and H4. |
| 0.9976 | Methylation | We also show that hSWI / SNF - associated PRMT5 can methylate hypoacetylated histones H3 and H4 more efficiently than Entityhyperacetylated histones H3 and EntityH4 . |
| 0.9921 | Methylation | We also show that hSWI / SNF - associated PRMT5 can methylate hypoacetylated histones H3 and H4 more efficiently than Entityhyperacetylated Entityhistones H3 and H4. |
| 0.9894 | Methylation | We also show that hSWI / SNF - associated PRMT5 can methylate Entityhypoacetylated histones H3 and EntityH4 more efficiently than hyperacetylated histones H3 and H4. |
| 0.9885 | Methylation | We also show that hSWI / SNF - associated PRMT5 can Entitymethylate hypoacetylated histones H3 and H4 more efficiently than hyperacetylated histones H3 and EntityH4 . |
| 0.9769 | Methylation | We also show that hSWI / SNF - associated PRMT5 can Entitymethylate hypoacetylated histones H3 and H4 more efficiently than hyperacetylated Entityhistones H3 and H4. |
| 0.9462 | Methylation | We also show that hSWI / SNF - associated PRMT5 can methylate Entityhypoacetylated Entityhistones H3 and H4 more efficiently than hyperacetylated histones H3 and H4. |
| 0.9985 | Methylation | We also show that hSWI / SNF - associated PRMT5 can Entitymethylate hypoacetylated histones H3 and EntityH4 more efficiently than hyperacetylated histones H3 and H4. |
| 0.9921 | Methylation | We also show that hSWI / SNF - associated PRMT5 can Entitymethylate hypoacetylated Entityhistones H3 and H4 more efficiently than hyperacetylated histones H3 and H4. |
| 0.9736 | Methylation | We also show that hSWI / SNF - associated EntityPRMT5 can Entitymethylate hypoacetylated histones H3 and H4 more efficiently than hyperacetylated histones H3 and H4. |
| 0.5937 | Methylation | We also show that hSWI / SNF - associated PRMT5 can Entitymethylate hypoacetylated histones H3 and H4 more efficiently than hyperacetylated histones H3 and EntityH4 . |
| 0.4155 | Methylation | We also show that hSWI / SNF - associated PRMT5 can Entitymethylate hypoacetylated histones H3 and H4 more efficiently than hyperacetylated Entityhistones H3 and H4. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | BACKGROUND : Centromeric domains often consist of repetitive elements that are assembled in specialized chromatin, characterized by Entityhypoacetylation of Entityhistones H3 and H4 and methylation of lysine 9 of histone H3 ( K9 - MeH3 ). |
| 0.9993 | Methylation | BACKGROUND : Centromeric domains often consist of repetitive elements that are assembled in specialized chromatin, characterized by hypoacetylation of histones H3 and H4 and Entitymethylation of Entitylysine 9 of histone H3 ( K9 - MeH3 ). |
| 0.9941 | Methylation | BACKGROUND : Centromeric domains often consist of repetitive elements that are assembled in specialized chromatin, characterized by Entityhypoacetylation of histones H3 and EntityH4 and methylation of lysine 9 of histone H3 ( K9 - MeH3 ). |
| 0.9978 | Methylation | BACKGROUND : Centromeric domains often consist of repetitive elements that are assembled in specialized chromatin, characterized by hypoacetylation of histones H3 and H4 and Entitymethylation of Entitylysine 9 of histone H3 ( K9 - MeH3 ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | Thermal stability and aggregation of sulfolobus solfataricus beta - glycosidase are dependent upon the EntityN - epsilon - methylation of specific Entitylysyl residues : critical role of in vivo post - translational modifications. |
| 1.0000 | Methylation | Thermal stability and aggregation of sulfolobus solfataricus beta - glycosidase are dependent upon the EntityN - epsilon - methylation of specific Entitylysyl residues : critical role of in vivo post - translational modifications. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9995 | Methylation | The aim of this work is to clarify some effects of methylation on the properties of Entitybeta - glycosidase from Sulfolobus solfataricus, by a structural comparison between the native, Entitymethylated protein and its unmethylated counterpart, recombinantly expressed in Escherichia coli. |
| 0.9989 | Methylation | The aim of this work is to clarify some effects of methylation on the properties of Entitybeta - glycosidase from Sulfolobus solfataricus, by a structural comparison between the native, methylated protein and its Entityunmethylated counterpart, recombinantly expressed in Escherichia coli. |
| 1.0000 | Methylation | The aim of this work is to clarify some effects of Entitymethylation on the properties of Entitybeta - glycosidase from Sulfolobus solfataricus, by a structural comparison between the native, methylated protein and its unmethylated counterpart, recombinantly expressed in Escherichia coli. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | These observations suggest a role for the Entitymethylation of Entitylysyl residues , located in selected domains, in the thermal stabilization of beta - glycosidase from S. solfataricus. |
| 0.9999 | Methylation | These observations suggest a role for the Entitymethylation of Entitylysyl residues, located in selected domains, in the thermal stabilization of beta - glycosidase from S. solfataricus. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9956 | Methylation | The von Hippel - Lindau ( VHL ) E3 ubiquitin ligase binds HIF - 1alpha through specific recognition of Entityhydroxylated Pro - 402 or EntityPro - 564 , both of which are modified by the oxygen - dependent HIF prolyl hydroxylases ( PHDs / HPHs ). |
| 0.9918 | Methylation | The von Hippel - Lindau ( VHL ) E3 ubiquitin ligase binds HIF - 1alpha through specific recognition of Entityhydroxylated EntityPro - 402 or Pro - 564, both of which are modified by the oxygen - dependent HIF prolyl hydroxylases ( PHDs / HPHs ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9971 | Methylation | We show here that the role of Leu - 574 is to recruit EntityPHD2 / HPH2 for Pro - 564 Entityhydroxylation . |
| 0.9956 | Methylation | We show here that the role of Leu - 574 is to recruit PHD2 / HPH2 for EntityPro - 564 Entityhydroxylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9957 | Methylation | An antibody specific for Entityhydroxylated EntityPro - 564 has been used to determine the hydroxylation status ; mutation or deletion of Leu - 574 results in a significant decrease in the ratio of the hydroxylated HIF - 1alpha to the total amount. |
| 0.9937 | Methylation | An antibody specific for hydroxylated Pro - 564 has been used to determine the hydroxylation status ; mutation or deletion of Leu - 574 results in a significant decrease in the ratio of the Entityhydroxylated EntityHIF - 1alpha to the total amount. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9969 | Methylation | The nine - residue spacing between Pro - 564 and Leu - 574 is not obligatory for Entityprolyl Entityhydroxylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9978 | Methylation | CONCLUSION : The Entitytransferrin microheterogeneity pattern shifted towards reduced Entityglycosylation and sialylation in addition to a decrease in total transferrin concentration in fetal blood compared to that of non - pregnant and pregnant women. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9993 | Methylation | Heterochromatin and Entitytri - methylated Entitylysine 20 of histone H4 in animals. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9989 | Methylation | EntityTri - methylated Entitylysine 20 on histone H4 ( Me ( 3 ) K20H4 ) is a marker of constitutive heterochromatin in murine interphase and metaphase cells. |
| 0.9968 | Methylation | EntityTri - methylated Entitylysine 20 on histone H4 ( Me ( 3 ) K20H4 ) is a marker of constitutive heterochromatin in murine interphase and metaphase cells. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | To understand the interplay between various Entityhistone modifications, including Entityacetylation and methylation, we performed a genome - wide chromatin structure analysis in a higher eukaryote. |
| 0.9990 | Methylation | To understand the interplay between various Entityhistone modifications, including acetylation and Entitymethylation , we performed a genome - wide chromatin structure analysis in a higher eukaryote. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being Entityhyperacetylated for EntityH3 and H4 and hypermethylated at Lys 4 and Lys 79 of H3, and inactive genes being hypomethylated and deacetylated at the same residues. |
| 0.9997 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and Entityhypermethylated at EntityLys 4 and Lys 79 of H3, and inactive genes being hypomethylated and deacetylated at the same residues. |
| 0.9991 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being Entityhyperacetylated for H3 and EntityH4 and hypermethylated at Lys 4 and Lys 79 of H3, and inactive genes being hypomethylated and deacetylated at the same residues. |
| 0.9828 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and Entityhypermethylated at Lys 4 and EntityLys 79 of H3, and inactive genes being hypomethylated and deacetylated at the same residues. |
| 0.8726 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and hypermethylated at EntityLys 4 and Lys 79 of H3, and inactive genes being Entityhypomethylated and deacetylated at the same residues. |
| 0.8613 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and hypermethylated at Lys 4 and EntityLys 79 of H3, and inactive genes being Entityhypomethylated and deacetylated at the same residues. |
| 0.7035 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and EntityH4 and hypermethylated at Lys 4 and Lys 79 of H3, and inactive genes being hypomethylated and Entitydeacetylated at the same residues. |
| 0.4697 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for EntityH3 and H4 and hypermethylated at Lys 4 and Lys 79 of H3, and inactive genes being hypomethylated and Entitydeacetylated at the same residues. |
| 0.9985 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and Entityhypermethylated at EntityLys 4 and Lys 79 of H3, and inactive genes being hypomethylated and deacetylated at the same residues. |
| 0.9500 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and Entityhypermethylated at Lys 4 and EntityLys 79 of H3, and inactive genes being hypomethylated and deacetylated at the same residues. |
| 0.6089 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and hypermethylated at Lys 4 and EntityLys 79 of H3, and inactive genes being Entityhypomethylated and deacetylated at the same residues. |
| 0.5887 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and hypermethylated at EntityLys 4 and Lys 79 of H3, and inactive genes being Entityhypomethylated and deacetylated at the same residues. |
| 0.4885 | Methylation | We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and EntityH4 and hypermethylated at Lys 4 and Lys 79 of H3, and inactive genes being Entityhypomethylated and deacetylated at the same residues. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9958 | Methylation | Less frequent Entitypromoter Entityhypermethylation of DLC - 1 gene in primary breast cancers. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9973 | Methylation | To determine the implication of aberrant methylation, one of the most frequent mechanisms of silencing the tumor suppressor or cancer - related genes, we examined the Entitymethylation status of DLC - 1 Entitypromoter region in breast cancer cell lines and primary breast tumors. |
| 0.9950 | Methylation | To determine the implication of aberrant methylation, one of the most frequent mechanisms of silencing the tumor suppressor or cancer - related genes, we examined the Entitymethylation status of DLC - 1 promoter Entityregion in breast cancer cell lines and primary breast tumors. |
| 0.9946 | Methylation | To determine the implication of aberrant methylation, one of the most frequent mechanisms of silencing the tumor suppressor or cancer - related genes, we examined the Entitymethylation status of DLC - 1 Entitypromoter region in breast cancer cell lines and primary breast tumors. |
| 0.4963 | Methylation | To determine the implication of aberrant Entitymethylation , one of the most frequent mechanisms of silencing the tumor suppressor or cancer - related genes, we examined the methylation status of DLC - 1 promoter Entityregion in breast cancer cell lines and primary breast tumors. |
| 0.4678 | Methylation | To determine the implication of aberrant Entitymethylation , one of the most frequent mechanisms of silencing the tumor suppressor or cancer - related genes, we examined the methylation status of DLC - 1 Entitypromoter region in breast cancer cell lines and primary breast tumors. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9992 | Methylation | The gene silencing by methylation was also confirmed by the re - expression of DLC - 1 by the 5 - aza - 2'- deoxycytidine treatment in EntityDLC - 1 Entityhypermethylated cell line. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | But the Entitymethylation of EntityDLC - 1 gene was less frequently shown in primary breast cancers ( 10 % ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | These data suggest that Entityhypermethylation is responsible for silencing of EntityDLC - 1 gene in a limited portion of breast cancers. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | EntityGlycosylation of the EntityENV spike of primate immunodeficiency viruses and antibody neutralization. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9998 | Methylation | This is thought to be a result of a combination of immunodominance of hypervariable regions of the Env protein that can easily escape neutralization, antibody reactivity to gp160 " decoy " protein in cell surface debris or monomeric gp120, conformational constraints within the Env trimer that create unfavorable antibody binding conditions and extensive Entityglycosylation of the exposed regions of EntityEnv within the trimer. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9985 | Methylation | Part of the strategy toward development of an optimally immunogenic Env spike will likely require modification of EntityEnv Entityglycosylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9994 | Methylation | The MSP assay detected Entityhypermethylation of p16 in 9 patients ( 22 % ), EntityE - cadherin in 9 patients ( 22 % ), and RARbeta in 6 patients ( 15 % ). |
| 0.9993 | Methylation | The MSP assay detected Entityhypermethylation of Entityp16 in 9 patients ( 22 % ), E - cadherin in 9 patients ( 22 % ), and RARbeta in 6 patients ( 15 % ). |
| 0.9988 | Methylation | The MSP assay detected Entityhypermethylation of p16 in 9 patients ( 22 % ), E - cadherin in 9 patients ( 22 % ), and EntityRARbeta in 6 patients ( 15 % ). |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9965 | Methylation | Human SWI / SNF - associated EntityPRMT5 Entitymethylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9992 | Methylation | We have recently shown that PRMT5 can interact with flag - tagged BRG1 - and hBRM - based hSWI / SNF chromatin remodelers and that both complexes can specifically Entitymethylate histones H3 and EntityH4 . |
| 0.9981 | Methylation | We have recently shown that PRMT5 can interact with flag - tagged BRG1 - and hBRM - based hSWI / SNF chromatin remodelers and that both complexes can specifically Entitymethylate Entityhistones H3 and H4. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9996 | Methylation | Here we report that PRMT5 can be found in association with endogenous hSWI / SNF complexes, which can methylate H3 and H4 N - terminal tails, and show that H3 arginine 8 and H4 arginine 3 are preferred sites of Entitymethylation by recombinant and hSWI / SNF - associated EntityPRMT5 . |
| 0.9996 | Methylation | Here we report that PRMT5 can be found in association with endogenous hSWI / SNF complexes, which can methylate H3 and H4 N - terminal tails, and show that H3 arginine 8 and H4 Entityarginine 3 are preferred sites of Entitymethylation by recombinant and hSWI / SNF - associated PRMT5. |
| 0.9957 | Methylation | Here we report that PRMT5 can be found in association with endogenous hSWI / SNF complexes, which can methylate H3 and H4 N - terminal tails, and show that H3 Entityarginine 8 and H4 arginine 3 are preferred sites of Entitymethylation by recombinant and hSWI / SNF - associated PRMT5. |
| 0.9879 | Methylation | Here we report that PRMT5 can be found in association with endogenous hSWI / SNF complexes, which can methylate H3 and H4 N - terminal tails, and show that H3 Entityarginine 8 and H4 arginine 3 are preferred sites of Entitymethylation by recombinant and hSWI / SNF - associated PRMT5. |
| 0.5024 | Methylation | Here we report that PRMT5 can be found in association with endogenous hSWI / SNF complexes, which can Entitymethylate H3 and H4 N - terminal tails, and show that H3 Entityarginine 8 and H4 arginine 3 are preferred sites of methylation by recombinant and hSWI / SNF - associated PRMT5. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | The hydrolysis and Entitytransglycosylation properties of EntityAmyM suggest that it has novel characteristics and can be regarded as an intermediate type of maltogenic amylase, alpha - amylase, and 4 - alpha - glucanotransferase. |
| 0.9714 | Methylation | The hydrolysis and Entitytransglycosylation properties of AmyM suggest that it has novel characteristics and can be regarded as an intermediate type of maltogenic amylase, alpha - amylase, and Entity4 - alpha - glucanotransferase . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9995 | Methylation | Histone Entitymethylation acts as an epigenetic regulator of chromatin activity through the modification of Entityarginine and lysine residues on histones H3 and H4. |
| 0.9981 | Methylation | Histone Entitymethylation acts as an epigenetic regulator of chromatin activity through the modification of arginine and Entitylysine residues on histones H3 and H4. |
| 0.9968 | Methylation | Histone Entitymethylation acts as an epigenetic regulator of chromatin activity through the modification of arginine and Entitylysine residues on histones H3 and H4. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 1.0000 | Methylation | To examine the potential developmental roles of these modifications, we determined the global patterns of lysine Entitymethylation involving EntityK9 on histone H3 and K20 on histone H4 in midgestation mouse embryos. |
| 0.9971 | Methylation | To examine the potential developmental roles of these modifications, we determined the global patterns of lysine Entitymethylation involving K9 on histone H3 and EntityK20 on histone H4 in midgestation mouse embryos. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9970 | Methylation | Interestingly, three of these Entitymodifications , histone H3 trimethyl EntityK9 , histone H4 monomethyl K20, and histone H4 trimethyl K20 exhibited marked differences in their distribution within the neuroepithelium. |
| 0.9966 | Methylation | Interestingly, three of these Entitymodifications , histone H3 trimethyl K9, histone H4 monomethyl EntityK20 , and histone H4 trimethyl K20 exhibited marked differences in their distribution within the neuroepithelium. |
| 0.9941 | Methylation | Interestingly, three of these Entitymodifications , histone H3 trimethyl K9, histone H4 monomethyl K20, and histone H4 trimethyl EntityK20 exhibited marked differences in their distribution within the neuroepithelium. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9991 | Methylation | Specifically, both histone H3 trimethyl K9 and H4 monomethyl K20 were elevated in proliferating cells of the neural tube, which in the case of the EntityK9 Entitymodification was limited to mitotic cells on the luminal surface. |
| 0.4343 | Methylation | Specifically, both histone H3 trimethyl K9 and H4 monomethyl EntityK20 were elevated in proliferating cells of the neural tube, which in the case of the K9 Entitymodification was limited to mitotic cells on the luminal surface. |
| 0.4136 | Methylation | Specifically, both histone H3 trimethyl EntityK9 and H4 monomethyl K20 were elevated in proliferating cells of the neural tube, which in the case of the K9 Entitymodification was limited to mitotic cells on the luminal surface. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9962 | Methylation | The inverse relationship of histone H4 EntityK20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the Entitytrimethyl modification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.9997 | Methylation | The inverse relationship of histone H4 EntityK20 Entitymethyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the trimethyl modification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.9964 | Methylation | The inverse relationship of histone H4 EntityK20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the trimethyl Entitymodification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.9932 | Methylation | The inverse relationship of histone H4 EntityK20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the Entitytrimethyl modification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.6355 | Methylation | The inverse relationship of histone H4 K20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the Entitytrimethyl modification Entitymodification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.5638 | Methylation | The inverse relationship of histone H4 K20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the Entitytrimethyl modification Entitymodification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.5345 | Methylation | The inverse relationship of histone H4 K20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the Entitytrimethyl Entitytrimethyl modification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.5077 | Methylation | The inverse relationship of histone H4 K20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the Entitytrimethyl Entitymodification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.4898 | Methylation | The inverse relationship of histone H4 K20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the Entitytrimethyl Entitymodification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| 0.4421 | Methylation | The inverse relationship of histone H4 K20 methyl derivatives is even more striking during skeletal and cardiac myogenesis where the accumulation of the Entitytrimethyl modification Entitytrimethyl modification in pericentromeric heterochromatin suggests a role in gene silencing in postmitotic muscle cells. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | Importantly, our results establish that histone Entitylysine Entitymethylation occurs in a highly dynamic manner that is consistent with their function in an epigenetic program for cell division and differentiation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9986 | Methylation | To investigate the effect of EGCG on H. pylori - induced toll - like receptor 4 ( TLR - 4 ) signaling, reverse transcription - polymerase chain reaction and Western blot analysis corresponding to Entityglycosylated EntityTLR - 4 were carried out. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9999 | Methylation | Helicobacter pylori infection stimulated the Entityglycosylation of EntityTLR - 4 , which initiates intracellular signaling in the infected host cell, but the pretreatment with EGCG completely blocked the TLR - 4 glycosylation. |
| 0.9993 | Methylation | Helicobacter pylori infection stimulated the glycosylation of TLR - 4, which initiates intracellular signaling in the infected host cell, but the pretreatment with EGCG completely blocked the EntityTLR - 4 Entityglycosylation . |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9959 | Methylation | EntityHistone H2B Entityubiquitylation is associated with elongating RNA polymerase II. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9936 | Methylation | Rad6 - mediated Entityubiquitylation of histone H2B at Entitylysine 123 has been linked to transcriptional activation and the regulation of lysine methylation on histone H3. |
| 0.9927 | Methylation | Rad6 - mediated ubiquitylation of histone H2B at lysine 123 has been linked to transcriptional activation and the regulation of Entitylysine Entitymethylation on histone H3. |
| 0.9764 | Methylation | Rad6 - mediated Entityubiquitylation of histone H2B at Entitylysine 123 has been linked to transcriptional activation and the regulation of lysine methylation on histone H3. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9985 | Methylation | However, how Rad6 and EntityH2B Entityubiquitylation contribute to the transcription and histone methylation processes is poorly understood. |
| 0.9977 | Methylation | However, how Rad6 and H2B ubiquitylation contribute to the transcription and Entityhistone Entitymethylation processes is poorly understood. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9945 | Methylation | This association appears to be necessary for the transcriptional activities of Rad6, as deletion of various Paf1 complex members or Bre1 abolishes EntityH2B Entityubiquitylation ( ubH2B ) and reduces the recruitment of Rad6 to the promoters and transcribed regions of active genes. |
| 0.7104 | Methylation | This association appears to be necessary for the transcriptional activities of Rad6, as deletion of various Paf1 complex members or Bre1 abolishes EntityH2B Entityubiquitylation ( ubH2B ) and reduces the recruitment of Rad6 to the promoters and transcribed regions of active genes. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9863 | Methylation | In support of a role for Rad6 - dependent EntityH2B Entityubiquitylation in transcription elongation, we find that ubH2B levels are dramatically reduced in strains bearing mutations of the Pol II C - terminal domain ( CTD ) and abolished by inactivation of Kin28, the serine 5 CTD kinase that promotes the transition from initiation to elongation. |
| 0.7766 | Methylation | In support of a role for EntityRad6 - dependent H2B Entityubiquitylation in transcription elongation, we find that ubH2B levels are dramatically reduced in strains bearing mutations of the Pol II C - terminal domain ( CTD ) and abolished by inactivation of Kin28, the serine 5 CTD kinase that promotes the transition from initiation to elongation. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9990 | Methylation | Finally, we show that Saccharomyces cerevisiae mutants bearing defects in the pathway to EntityH2B Entityubiquitylation display transcription elongation defects as assayed by 6 - azauracil sensitivity. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|
| 0.9982 | Methylation | Collectively, our results indicate a role for Rad6 and EntityH2B Entityubiquitylation during the elongation cycle of transcription and suggest a mechanism by which H3 methylation may be regulated. |
| 0.9982 | Methylation | Collectively, our results indicate a role for Rad6 and H2B ubiquitylation during the elongation cycle of transcription and suggest a mechanism by which EntityH3 Entitymethylation may be regulated. |
| Score | Relation | Text (Head - Tail) |
|---|---|---|